Measurement of Cyclic Flows in Trachea Using PIV and Numerical simulation

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Date
2015-05-06
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Mark
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EDP Sciences
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Abstract
Inhalation of pharmaceutical aerosols is a convenient way to treat lung or even systemic diseases. For effective treatment it is very important to understand air flow characteristics within respiratory airways and determine deposition hot spots. In this paper the air flow in trachea was investigated by numerical simulations. To validate these results we carried out particle image velocimetry experiments and compared resulting velocity fields. Simplified geometry of respiratory airways from oral cavity to 4th generation of branching was employed. Air flow characteristics were analysed during sinusoidal breathing pattern for light activity conditions (period 4 s and tidal volume 1 l). The observed flow fields indicated that the flow in trachea is turbulent during the sinusoidal flow except phases of flow turnarounds. The flow was skewed to front side of the trachea during inspiration and had twin-peak profile during expiration because of the mixing from daughter branches. The methods were compared and good agreement was found. This validation of CFD simulation can result into its further usage in respiratory airflow studies.
Inhalace farmaceutických aerosolů je pohodlný způsob, kterým se lečí dýchací obtíže. Pro efektivní léčbu je potřeba přivést aerosol na předem určené místo a k tomu je nutné dobře porozumět proudění v dýchacích cestách. V tomto článku byl studováno proudění v průdušnici za pomoci PIV a CFD. Byla snaha validovat výsledky simulací pomocí experimentu. Proudění se měřilo v zjednodušeném modelu plic během sinusoidového dechového režimu. Byla nalezena dobrá shoda, což povedeno k dalšímu použití CFD při studiu proudění v plicích.
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en
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Creative Commons Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
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