MILANOVIC, S. Numerický model dýchání [online]. Brno: Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. 2017.
The aim of Selena Milanovic's thesis is to create a numerical model of inhalation, to create a tracheal model and to describe and measure the distribution of nanoparticles in the inhalation process. The work follows the research of Alveopic project at BUT and FH Technikum Wien. The student conducted her research as a part of the thesis in both Vienna and Brno as a double degree study program. The work includes a 3D model design that is printed on a 3D printer and plugged into the i-Lung simulator. Further, the thesis describes the distribution of nanoparticles in the inhalation process. The results are discussed at the end. I find the work in accordance and therefore I have no technical comments. The student has consulted her work with supervisor regularly. The work is provided correctly without operational failures. As a supervisor I evaluate the thesis by Selena Milanovic with the mark "Excellent" / A.
The task of Miss Selena Milanovic was as follows: 1) Study physiology of a human respiratory system. Focus on function of lungs and related respiratory processes. Study a simulator - pulmonary lung module developed within AlveoPic project at Brno University of Technology. 2) Study and design a three-dimensional model of trachea. 3) Create and describe in detail a flow model of inhalation. 4) Design a three-dimensional model of inhalation in trachea and realize its numerical model. 5) Simulate the respiratory processes using the model and prove that the numerical simulation corresponds to the realized model. Students fulfilled all the tasks successfully. In the first task she studied physiology of a human respiratory. She went from comprehensive references, titled in the end of the diploma thesis. The study has been oriented into the topic of function of lungs and related respiratory processes. Student shows that she has a good anatomical background, she describes and explains basic of the anatomy of the breathing process and shows it in Figures 1.3, and Fig 1.4. She has given attention to the basic problem of the study – influences of aerosols and particles during breathing on the human airways. The next parts of the Chapter 1 deal with particle deposition in airways and the state of the art modelling of this process. In the sub – chapter 1.7 student deals with the electromechanical model of the breathing process. Student presents technical solution of the i - LUNG model, which has been developed in the FH Technikum Wien in cooperation with the Polytechic of Jihlava and the Brno University of Technology. In the Chapt. 2 student conducts studies of the particle flow and deposition was with two approaches: numerical simulation and experimental validation. At first, realistic modeling of human airways was attempted. Subsequently, numerical models of the i-Lung's airways were realized and a CFD analysis of aerosol flow was conducted. Validation of the results achieved through simulations was obtained by realizing a suitable experimental setup specified in the block diagram in the Fig. 2.3 and the Fig. 2.4. In the Chapt. 2.2 there is specified the experimental validation procedure which has been done on pig lungs, situated into the respiratory box of the i-lung simulator for defined time. Block diagram of the experimental setup used for particle flow and deposition analysis is in the Fig. 2.3. The testing procedure is described in the Chapt. 2.2.2 and I have no objection against it. In the Chapt 3 there are described and compared results from the numerical analyses and the experimental study of aerosols flow and practical deposition. Results are shown in Fig. 3.7, 3.8 and 3.9. The statistical distribution of particle size is shown in Fig. 3.10, 3.11 and 3.12. Student provided numerous experiments and the statistical data can be considered positive. In the Chapt 4 there are discussed the obtained data from measurements and numerical analyses. The diploma thesis ends with a comprehensive reference list. The work is provided correctly without methodological failures. Student demonstrates a very good theoretical background in the biomechanical engineering and she understands also to the technical solution of i-Lung simulator. Nevertheless I have following objection against the written report: - The Abstract is the weakest part of the report, its contents does not speak at all about the research and experimental works which are described well in the report - In the list of references there are missing numerous contributions from proceedings of international conferences and papers in magazines describing research as well experiments and their scientific – technical background in a direct link with the i-Lung simulator Evaluation: A/ 90 ECTS credits
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