Now showing items 1-6 of 6

  • Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery 

    Blažková, Iva; Nguyen, Hoai Viet; Dostálová, Simona; Kopel, Pavel; Stanisavljevic, Maja; Vaculovičová, Markéta; Stiborová, Marie; Eckschlager, Tomáš; Kizek, René; Adam, Vojtěch (MDPI, 2013-06-27)
    Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation ...
  • The Composites of Graphene Oxide with Metal or Semimetal Nanoparticles and Their Effect on Pathogenic Microorganisms 

    Richtera, Lukáš; Hegerová, Dagmar; Číhalová, Kristýna; Kremplová, Monika; Milosavljević, Vedran; Kopel, Pavel; Blažková, Iva; Hynek, David; Adam, Vojtěch; Kizek, René (MDPI, 2015-06-01)
    The present experiment describes a synthesis process of composites based on graphene oxide, which was tested as a carrier for composites of metal- or metalloid-based nanoparticles (Cu, Zn, Mn, Ag, AgP, Se) and subsequently ...
  • Effect of Ampicillin, Streptomycin, Penicillin and Tetracycline on Metal Resistant and Non-Resistant Staphylococcus aureus 

    Hegerová, Dagmar; Dostálová, Simona; Blažková, Iva; Michálek, Petr; Ruttkay-Nedecký, Branislav; Sklenář, Matěj; Nejdl, Lukáš; Kudr, Jiří; Gumulec, Jaromír; Tmejová, Kateřina; Konečná, Marie; Vaculovičová, Markéta; Hynek, David; Masařík, Michal; Kynický, Jindřich; Kizek, René; Adam, Vojtěch (MDPI AG, POSTFACH, 2014-03-19)
    There is an arising and concerning issue in the field of bacterial resistance, which is confirmed by the number of deaths associated with drug-resistant bacterial infections. The aim of this study was to compare the effects ...
  • Lead Ions Encapsulated in Liposomes and Their Effect on Staphylococcus aureus 

    Kenšová, Renáta; Blažková, Iva; Konečná, Marie; Kopel, Pavel; chudobova, Dagmar; Zítka, Ondřej; Vaculovičová, Markéta; Hynek, David; Adam, Vojtěch; Beklová, Miroslava; Kizek, René (MDPI, 2013-12-01)
    The aim of the study was the preparation of a liposome complex with encapsulated lead ions, which were electrochemically detected. In particular, experiments were focused on the potential of using an electrochemical method ...
  • A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Kudr, Jiří; Gumulec, Jaromír; Blažková, Iva; Zítka, Ondřej; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch; Kizek, René (MDPI, 2013-11-01)
    Doxorubicin is a commonly used antineoplastic agent in the treatment of many types of cancer. Little is known about the interactions of doxorubicin with cardiac biomolecules. Serious cardiotoxicity including dilated ...
  • Simultaneous Automatic Electrochemical Detection of Zinc, Cadmium, Copper and Lead Ions in Environmental Samples Using a Thin-Film Mercury Electrode and an Artificial Neural Network 

    Kudr, Jiří; Nguyen, Hoai Viet; Gumulec, Jaromír; Nejdl, Lukáš; Blažková, Iva; Ruttkay-Nedecký, Branislav; Hynek, David; Kynický, Jindřich; Adam, Vojtěch; Kizek, René (MDPI, 2015-01-01)
    In this study a device for automatic electrochemical analysis was designed. A three electrodes detection system was attached to a positioning device, which enabled us to move the electrode system from one well to another ...