Now showing items 1-3 of 3

  • Differences in siRNA encapsulation between HsaHFt-RK ferritin and EcaLHFt 

    Charousová, Markéta; Mokrý, Michal; Pekařík, Vladimír (Mendel University in Brno, 2019-12-31)
    Nanomedicine in cancer treatment has a great potential. With usage of proper nanocarrier we would be able to eliminate negative side effects and excessively high toxicity of chemotherapeutical drugs to normal cells. Ferritins ...
  • Effect of apoferritin surface-biomacromolecular modification on cellular uptake and inhibition of protein corona 

    Tesařová, Barbora; Dostálová, Simona; Charousová, Markéta; Škubalová, Zuzana; Guráň, Roman; Do, Tomáš; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2019-01-02)
    The effects of surface modifications (PEGylation and PASylation) of natural nanocarriers based on apoferritin (FRT) were tested in this work. The main goals of performed PEGylation/PASylation were decreased protein corona ...
  • hNET as a target for neuroblastoma nanomedicine 

    Charousová, Markéta; Dostálová, Simona; Haddad, Yazan Abdulmajeed Eyadh; Strmiska, Vladislav; Křížková, Soňa; Hynek, David; Milosavljević, Vedran; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    Chemotherapy often results in various side effects, which can negatively affect health. Neuroblastoma, one of the most common types of childhood cancer, is but one of the examples, where side effects of chemotherapeutic ...