Now showing items 1-7 of 7

  • Anticancerogenic effect of spices due to phenolic and flavonoid compounds – in vitro evaluation on prostate cells 

    Lacková, Zuzana; Buchtelová, Hana; Buchtová, Žaneta; Klejdus, Bořivoj; Heger, Zbyněk; Brtnický, Martin; Kynický, Jindřich; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2017-09-28)
    This study shows the effects of spices, and their phenolic and flavonoid compounds, on prostate cell lines (PNT1A, 22RV1 and PC3). The results of an MTT assay on extracts from eight spices revealed the strongest inhibitory ...
  • Antioxidant response of arabidopsis thaliana to ZnSe-nanoparticles, selenium and zinc ions 

    Koláčková, Martina; Moulick, Amitava; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    The impact of zinc selenide nanoparticles (ZnSe-NPs) on plants is still unknown. The intention of this work was to compare phytotoxicity of ZnSe-NPs and selenium and zinc ions in 100, 250 and 500 M concentrations. Young ...
  • Effect of lycorine on the green algae Chlamydomonas reinhardtii under UV-C irradiation 

    Koláčková, Martina; Dvořák, Marek; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2019-01-02)
    Lycorin (LYC) is an inhibitor of the growth in higher plants through the inhibition of the last step of ascorbic acid biosynthesis. Ascorbates are mainly involved in regulation of intracellular levels reactive oxygen ...
  • Effect of zinc-selenium nanoparticles on microalgae scenedesmus quadricauda 

    Strejčková, Aneta; Koláčková, Martina; Vaněčková, Tereza; Bytešníková, Zuzana; Moulick, Amitava; Rankić, Ivan; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    The increasing industrial use of nanomaterials in recent years poses a potential risk to the environment. The first organisms that come into contact with these substances include aquatic organisms, and therefore this study ...
  • Evaluation of Antioxidant Activity, Polyphenolic Compounds, Amino Acids and Mineral Elements of Representative Genotypes of Lonicera edulis 

    Sochor, Jiří; Juříková, Tunde; Pohanka, Miroslav; Škutková, Helena; Baroň, Mojmír; Tomášková, Lenka; Balla, Štefan; Klejdus, Bořivoj; Pokluda, Robert; Mlček, Jiří; Trojáková, Zuzana; Šaloun, Jan (MDPI, 2014-05-21)
    The aim of this study was to evaluate the bioactive substances in 19 berry cultivars of edible honeysuckle (Lonicera edulis). A statistical evaluation was used to determine the relationship between the content of selected ...
  • Optimalization of DNA isolation process in freshwater microalgae using homogenizer 

    Bačová, Romana; Koláčková, Martina; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    Last decades microalgae are gaining much interest due to high-valued biomolecules content. Increasing number of genetic studies and modifications require quality input material and short time analysis at the same time. ...
  • Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe-Dnmts axis 

    Strmiska, Vladislav; Michálek, Petr; Lacková, Zuzana; Guráň, Roman; Křížková, Soňa; Pompeiano Vaníčková, Lucie; Zítka, Ondřej; Stiborová, Marie; Eckschlager, Tomáš; Klejdus, Bořivoj; Pacík, Dalibor; Tvrdíková, Eliška; Keil, Claudia; Haase, Hajo; Adam, Vojtěch; Heger, Zbyněk (FEBS Press, 2019-05-31)
    DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells ...