Browsing by Author "Kynický, Jindřich"
Now showing items 1-12 of 12
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A 3D Microfluidic Chip for Electrochemical Detection of Hydrolysed Nucleic Bases by a Modified Glassy Carbon Electrode
Vlachová, Jana; Tmejová, Kateřina; Kopel, Pavel; Korabík, Michal; Zítka, Jan; Hynek, David; Kynický, Jindřich; Adam, Vojtěch; Kizek, René (MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, 2015-02-01)Modification of carbon materials, especially graphene-based materials, has wide applications in electrochemical detection such as electrochemical lab-on-chip devices. A glassy carbon electrode (GCE) modified with chemically ... -
Amalgam electrode-based electrochemical detector for on-site direct determination of cadmium(II) and lead(II) from soils
Nejdl, Lukáš; Kynický, Jindřich; Brtnický, Martin; Vaculovičová, Markéta; Adam, Vojtěch (MDPI, 2017-08-01)Toxic metal contamination of the environment is a global issue. In this paper, we present a low-cost and rapid production of amalgam electrodes used for determination of Cd(II) and Pb(II) in environmental samples (soils ... -
Anticancerogenic effect of spices due to phenolic and flavonoid compounds – in vitro evaluation on prostate cells
Lacková, Zuzana; Buchtelová, Hana; Buchtová, Žaneta; Klejdus, Bořivoj; Heger, Zbyněk; Brtnický, Martin; Kynický, Jindřich; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2017-09-28)This study shows the effects of spices, and their phenolic and flavonoid compounds, on prostate cell lines (PNT1A, 22RV1 and PC3). The results of an MTT assay on extracts from eight spices revealed the strongest inhibitory ... -
Behaviour of zinc complexes and zinc sulphide nanoparticles revealed by using screen printed electrodes and spectrometry
Nejdl, Lukáš; Ruttkay-Nedecký, Branislav; Kudr, Jiří; Kremplová, Monika; Cernei, Natalia Vladimirovna; Prášek, Jan; Konečná, Marie; Hubálek, Jaromír; Zítka, Ondřej; Kynický, Jindřich; Kopel, Pavel; Kizek, René; Adam, Vojtěch (MDPI AQ, 2013-10-25)In this study, we focused on microfluidic electrochemical analysis of zinc complexes (Zn(phen)(his)Cl-2, Zn(his)Cl-2) and ZnS quantum dots (QDs) using printed electrodes. This method was chosen due to the simple (easy to ... -
Bio-Sensing of Cadmium(II) Ions Using Staphylococcus aureus
Sochor, Jiří; Zítka, Ondřej; Hynek, David; Krejčová, Ludmila; Trnková, Libuše; Adam, Vojtěch; Hubálek, Jaromír; Kynický, Jindřich; Vrba, Radimír; Kizek, René (MDPI, 2011-11-08)Cadmium, as a hazardous pollutant commonly present in the living environment, represents an important risk to human health due to its undesirable effects (oxidative stress, changes in activities of many enzymes, interactions ... -
Complexes of silver(I) ions and silver phosphate nanoparticles with hyaluronic acid and/or chitosan as promising antimicrobial agents for vascular grafts
Hegerová, Dagmar; Nejdl, Lukáš; Gumulec, Jaromír; Kryštofová, Olga; Merlos Rodrigo, Miguel Ángel; Kynický, Jindřich; Ruttkay-Nedecký, Branislav; Kopel, Pavel; Babula, Petr; Adam, Vojtěch; Kizek, René (MDPI, 2013-06-28)Polymers are currently widely used to replace a variety of natural materials with respect to their favourable physical and chemical properties, and due to their economic advantage. One of the most important branches of ... -
Effect of Ampicillin, Streptomycin, Penicillin and Tetracycline on Metal Resistant and Non-Resistant Staphylococcus aureus
Hegerová, Dagmar; Dostálová, Simona; Blažková, Iva; Michálek, Petr; Ruttkay-Nedecký, Branislav; Sklenář, Matěj; Nejdl, Lukáš; Kudr, Jiří; Gumulec, Jaromír; Tmejová, Kateřina; Konečná, Marie; Vaculovičová, Markéta; Hynek, David; Masařík, Michal; Kynický, Jindřich; Kizek, René; Adam, Vojtěch (MDPI AG, POSTFACH, 2014-03-19)There is an arising and concerning issue in the field of bacterial resistance, which is confirmed by the number of deaths associated with drug-resistant bacterial infections. The aim of this study was to compare the effects ... -
Flow Injection Analysis with Electrochemical Detection for Rapid Identification of Platinum-Based Cytostatics and Platinum Chlorides in Water
Komínková, Markéta; Heger, Zbyněk; Zítka, Ondřej; Kynický, Jindřich; Pohanka, Miroslav; Beklová, Miroslava; Adam, Vojtěch; Kizek, René (MDPI, 2014-02-04)Platinum-based cytostatics, such as cisplatin, carboplatin or oxaliplatin are widely used agents in the treatment of various types of tumors. Large amounts of these drugs are excreted through the urine of patients into ... -
Microwave-assisted synthesis of goethite nanoparticles used for removal of Cr(VI) from aqueous solution
Nguyen, Dính Vinh; Kynický, Jindřich; Ambrožová, Pavlína; Adam, Vojtěch (MDPI, 2017-07-01)The microwave-assisted synthesis of goethite nanoparticles has been studied. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential ... -
Simultaneous Automatic Electrochemical Detection of Zinc, Cadmium, Copper and Lead Ions in Environmental Samples Using a Thin-Film Mercury Electrode and an Artificial Neural Network
Kudr, Jiří; Nguyen, Hoai Viet; Gumulec, Jaromír; Nejdl, Lukáš; Blažková, Iva; Ruttkay-Nedecký, Branislav; Hynek, David; Kynický, Jindřich; Adam, Vojtěch; Kizek, René (MDPI, 2015-01-01)In this study a device for automatic electrochemical analysis was designed. A three electrodes detection system was attached to a positioning device, which enabled us to move the electrode system from one well to another ... -
Study of Linkage between Glutathione Pathway and the Antibiotic Resistance of Escherichia coli from Patients Swab
Komínková, Markéta; Michálek, Petr; Číhalová, Kristýna; Guráň, Roman; Cernei, Natalia Vladimirovna; Nejdl, Lukáš; Šmerková, Kristýna; Dostálová, Simona; Hegerová, Dagmar; Heger, Zbyněk; Veselý, Radek; Gumulec, Jaromír; Kynický, Jindřich; Xhaxhiu, Kledi; Zítka, Ondřej; Adam, Vojtěch; Kizek, René (MDPI, 2015-03-31)In this work, we focused on the differences between bacterial cultures of E. coli obtained from swabs of infectious wounds of patients compared to laboratory E. coli. In addition, blocking of the protein responsible for ... -
Study of Linkage between Glutathione Pathway and the Antibiotic Resistance of Escherichia coli from Patients’ Swabs
Komínková, Markéta; Kizek, René; Michálek, Petr; Číhalová, Kristýna; Guráň, Roman; Cernei, Natalia Vladimirovna; Nejdl, Lukáš; Šmerková, Kristýna; Dostálová, Simona; chudobova, Dagmar; Heger, Zbyněk; Veselý, Radek; Gumulec, Jaromír; Kynický, Jindřich; Xhaxhiu, Kledi; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2015-05-31)In this work, we focused on the differences between bacterial cultures of E. coli obtained from swabs of infectious wounds of patients compared to laboratory E. coli. In addition, blocking of the protein responsible for ...