Now showing items 1-14 of 14

  • Biogenic amines modified carbon quantum dots as antibacterial agent 

    Gagić, Milica; Kočiová, Silvia; Richtera, Lukáš; Šmerková, Kristýna; Milosavljević, Vedran (Mendel University in Brno, 2019-12-31)
    An alternative to conventional way is needed to treat multiple drug resistant bacteria. In this work, four different amine modified carbon quantum dots (CQDs) were obtained by microwave irradiation treatment. The four ...
  • Characterization and in vitro analysis of probiotic-derived peptides against multi drug resistance bacterial infections 

    Mazumdar, Aninda; Haddad, Yazan Abdulmajeed Eyadh; Sur, Vishma Pratap; Milosavljević, Vedran; Bhowmick, Sukanya; Michálková, Hana; Guráň, Roman; Veselý, Radek; Moulick, Amitava (Frontiers Media, 2020-08-25)
    An inexorable switch from antibiotics has become a major desideratum to overcome antibiotic resistance. Bacteriocin fromLactobacillus casei, a cardinal probiotic was used to design novel antibacterial peptides named as ...
  • The Composites of Graphene Oxide with Metal or Semimetal Nanoparticles and Their Effect on Pathogenic Microorganisms 

    Richtera, Lukáš; Hegerová, Dagmar; Číhalová, Kristýna; Kremplová, Monika; Milosavljević, Vedran; Kopel, Pavel; Blažková, Iva; Hynek, David; Adam, Vojtěch; Kizek, René (MDPI, 2015-06-01)
    The present experiment describes a synthesis process of composites based on graphene oxide, which was tested as a carrier for composites of metal- or metalloid-based nanoparticles (Cu, Zn, Mn, Ag, AgP, Se) and subsequently ...
  • Designing a Composite Films Based on Carbon Quantum Dots and Furcellaran 

    Milosavljević, Vedran; Jamroz, Ewelina; Gagić, Milica; Kopel, Pavel; Adam, Vojtěch (TANGER, 2019-02-01)
    Composite films based on furcellaran (FUR) and carbon quantum dots (CQDs) has been obtained by casting method. The effects of CQDs films as nanofiller on optical, physical, mechanical and microstructural properties of ...
  • hNET as a target for neuroblastoma nanomedicine 

    Charousová, Markéta; Dostálová, Simona; Haddad, Yazan Abdulmajeed Eyadh; Strmiska, Vladislav; Křížková, Soňa; Hynek, David; Milosavljević, Vedran; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    Chemotherapy often results in various side effects, which can negatively affect health. Neuroblastoma, one of the most common types of childhood cancer, is but one of the examples, where side effects of chemotherapeutic ...
  • Isolation of histamine using -Fe2O3 nanoparticles 

    Gagić, Milica; Kopel, Pavel; Milosavljević, Vedran; Cernei, Natalia Vladimirovna; Zítka, Ondřej; Švec, Pavel; Jamroz, Ewelina; Adam, Vojtěch (Mendel University in Brno, 2019-01-02)
    Histamine, biologically active amine, is normally present in the body and it is involved in a local regulation of physiological processes. It occurs in food as a product of microbial decarboxylation of the amino acid ...
  • Nanocomposite furcellaran films - The influence of nanofillers on functional properties of furcellaran films and effect on linseed oil preservation 

    Jamroz, Ewelina; Kopel, Pavel; Tkaczewska, Joanna; Dordevič, Dani; Jančíková, Simona; Kulawik, Piotr; Milosavljević, Vedran; Doleželíková, Kristýna; Šmerková, Kristýna; Švec, Pavel; Adam, Vojtěch (MDPI, 2019-12-09)
    Nanocomposite films that were based on furcellaran (FUR) and nanofillers (carbon quantum dots (CQDs), maghemite nanoparticles (MAN), and graphene oxide (GO)) were obtained by the casting method. The microstructure, as well ...
  • Norepinephrine Transporter-Derived Homing Peptides Enable Rapid Endocytosis of Drug Delivery Nanovehicles into Neuroblastoma Cells 

    Haddad, Yazan Abdulmajeed Eyadh; Charousová, Markéta; Životská, Hana; Šplíchal, Zbyněk; Merlos Rodrigo, Miguel Ángel; Michálková, Hana; Křížková, Soňa; Tesařová, Barbora; Richtera, Lukáš; Vítek, Petr; Stokowa-Soltys, Kamila; Hynek, David; Milosavljević, Vedran; Rex, Simona; Heger, Zbyněk (BioMed Central, 2020-07-13)
    Background: Currently, the diagnosis and treatment of neuroblastomas-the most frequent solid tumors in children-exploit the norepinephrine transporter (hNET) via radiolabeled norepinephrine analogs. We aim to develop a ...
  • A novel biocompatible titanium–gadolinium quantum dot as a bacterial detecting agent with high antibacterial activity 

    Sur, Vishma Pratap; Mazumdar, Aninda; Amirmansoor, Ashrafi; Mukherjee, Atripan; Milosavljević, Vedran; Michálková, Hana; Kopel, Pavel; Richtera, Lukáš; Moulick, Amitava (MDPI, 2020-04-17)
    In this study, the titanium gadolinium quantum dots (TGQDs) were novel, first of its type to be synthesized, and fully characterized to date. Multiple physical characterization includes scanning electron microscopy (SEM), ...
  • Novel Vancomycin-Peptide Conjugate as Potent Antibacterial Agent against Vancomycin-Resistant Staphylococcus aureus 

    Jelínková, Pavlína; Šplíchal, Zbyněk; Jimenez Jimenez, Ana Maria; Haddad, Yazan Abdulmajeed Eyadh; Mazumdar, Aninda; Sur, Vishma Pratap; Milosavljević, Vedran; Kopel, Pavel; Buchtelová, Hana; Guráň, Roman; Zítka, Ondřej; Richtera, Lukáš; Hegerová, Dagmar; Heger, Zbyněk; Moulick, Amitava; Adam, Vojtěch (Dove Press, 2018-11-01)
    Background: Increase in vancomycin (Van)-resistant bacterial strains including vancomycin-resistant Staphylococcus aureus (VRSA) and lack of new effective antibiotics have become a formidable health problem. Materials and ...
  • Peptide-carbon quantum dots conjugate, derived from human Retinoic Acid Receptor Responder Protein 2, against antibiotic-resistant gram positive and gram negative pathogenic bacteria 

    Mazumdar, Aninda; Haddad, Yazan Abdulmajeed Eyadh; Milosavljević, Vedran; Michálková, Hana; Guráň, Roman; Bhowmick, Sukanya; Moulick, Amitava (MDPI, 2020-02-28)
    Antibiotic-resistant bacterial infections have become global issues for public health, which increases the utter need to develop alternatives to antibiotics. Here, the HSER (Homo sapiens retinoic acid receptor) peptide was ...
  • Using CdTe/ZnSe core/shell quantum dots to detect DNA and damage to DNA 

    Moulick, Amitava; Milosavljević, Vedran; Vlachová, Jana; Hynek, David; Podgajny, Robert; Kopel, Pavel; Adam, Vojtěch (Dove Medical Press, 2017-02-14)
    CdTe/ZnSe core/shell quantum dot (QD), one of the strongest and most highly luminescent nanoparticles, was directly synthesized in an aqueous medium to study its individual interactions with important nucleobases (adenine, ...
  • Zinc phosphate-based nanoparticles as a novel antibacterial agent: in vivo study on rats after dietary exposure 

    Horký, Pavel; Skaličková, Sylvie; Urbánková, Lenka; Baholet, Daria; Kočiová, Silvia; Bytešníková, Zuzana; Kabourková, Eliška; Lacková, Zuzana; Cernei, Natalia Vladimirovna; Gagić, Milica; Milosavljević, Vedran; Smolíková, Vendula; Václavková, Eva; Nevrkla, Pavel; Knot, Pavel; Kryštofová, Olga; Hynek, David; Kopel, Pavel; Skládanka, Jiří; Adam, Vojtěch; Šmerková, Kristýna (BioMed Central, 2019-02-12)
    Background: Development of new nanomaterials that inhibit or kill bacteria is an important and timely research topic. For example, financial losses due to infectious diseases, such as diarrhea, are a major concern in ...
  • The Zinc-Schiff Base-Novicidin Complex as a Potential Prostate Cancer Therapy 

    Milosavljević, Vedran; Haddad, Yazan Abdulmajeed Eyadh; Merlos Rodrigo, Miguel Ángel; Moulick, Amitava; Polanská, Hana; Hynek, David; Heger, Zbyněk; Kopel, Pavel; Adam, Vojtěch (PLOS, 2016-10-11)
    Prostate cancer cells control energy metabolism by chelating intracellular zinc. Thus, zinc delivery has been a popular therapeutic approach for prostate cancer. Here, we propose the use of the membrane-penetrating peptide ...