Now showing items 1-5 of 5

  • The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease 

    Roy, Sudeep; Gumulec, Jaromír; Kumar, Akhil; Raudenská, Martina; Baig, Mohd Hassan; Polanská, Hana; Balvan, Jan; Gupta, Mansi; Babula, Petr; Odstrčilík, Jan; Choi, Inho; Provazník, Ivo; Masařík, Michal (Wiley Periodicals, 2017-08-15)
    Metallothioneins (MTs) are a class of ubiquitously occurring low-molecular-weight cysteine- and metal-rich proteins containing sulfur-based metal clusters. MT-3 exhibits neuro-inhibitory activity. The possibility to enhance ...
  • Metallothionein – Immunohistochemical Cancer Biomarker: A Meta-Analysis 

    Gumulec, Jaromír; Raudenská, Martina; Adam, Vojtěch; Kizek, René; Masařík, Michal (PLOS, 2014-01-08)
    Metallothionein (MT) has been extensively investigated as a molecular marker of various types of cancer. In spite of the fact that numerous reviews have been published in this field, no meta-analytical approach has been ...
  • Oxidative Stress Resistance in Metastatic Prostate Cancer: Renewal by Self-Eating 

    Balvan, Jan; Gumulec, Jaromír; Raudenská, Martina; Křížová, Aneta; Štěpka, Petr; Babula, Petr; Kizek, René; Adam, Vojtěch; Masařík, Michal (PLOS, 2015-12-15)
    Resistant cancer phenotype is a key obstacle in the successful therapy of prostate cancer. The primary aim of our study was to explore resistance mechanisms in the advanced type of prostate cancer cells (PC-3) and to clarify ...
  • Prognostic Significance of Serum Free Amino Acids in Head and Neck Cancers 

    Všianský, Vít; Svobodová, Markéta; Gumulec, Jaromír; Cernei, Natalia Vladimirovna; Štěrbová, Dagmar; Zítka, Ondřej; Kostřica, Rom; Smilek, Pavel; Plzák, Jan; Betka, Jan; Kalfert, David; Masařík, Michal; Raudenská, Martina (MDPI, 2019-05-31)
    Despite distinctive advances in the field of head and neck squamous cell cancer (HNSCC) biomarker discovery, the spectrum of clinically useful prognostic serum biomarkers is limited. As metabolic activities in highly ...
  • Přírodní látky v léčbě rakoviny a jejich cytotoxicita 

    Hájková, Tereza
    Práce se zabývá problematikou přírodních látek v souvislosti s nádorovým onemocněním. Přírodní látky mají pozitivní vliv na lidský organismus a jsou schopné ovlivňovat životaschopnost a růst nádorových buněk. Hlavním ...