Now showing items 1-5 of 5

  • Application of the Enzymatic Electrochemical Biosensors for Monitoring Non-Competitive Inhibition of Enzyme Activity by Heavy Metals 

    Amirmansoor, Ashrafi; Sýs, Milan; Sedláčková, Eliška; Farag, Amir Shaaban; Adam, Vojtěch; Přibyl, Jan; Richtera, Lukáš (MDPI, 2019-07-03)
    The inhibition effect of the selected heavy metals (Ag+, Cd2+, Cu2+, and Hg2+) on glucose oxidase (GOx) enzyme from Aspergillus niger (EC 1.1.3.4.) was studied using a new amperometric biosensor with an electrochemical ...
  • Determination of arsenic bioavailability in mineral springs in the Czech Republic 

    Smolíková, Vendula; Sedláčková, Eliška; Pelcová, Pavlína; Ridošková, Andrea; Müllerová, Barbora (Mendel University in Brno, 2019-12-31)
    Mineral springs Hronovka and Regnerka located in the northeast Bohemia, Czech Republic are characteristic for high content of arsenic. The diffusive gradient in thin films technique (DGT) was used for determination of ...
  • Influence of liposomal platinum cytostatics on cancer cells by voltammetric methods 

    Sedláčková, Eliška; Laníková, Petra; Hynek, David; Krejčová, Ludmila; Buchtelová, Hana; Richtera, Lukáš; Adam, Vojtěch (TANGER, 2018-03-31)
    Aim of this work deals with closing of cisplatin into liposomes, the study of their stability and interaction with cancer cell lines. Commercial cisplatin cytostatic was encapsulated into three types of liposomes (L8, L10 ...
  • Sensitive biosensor for detection oncogenic miRNA-21 

    Vaňová, Veronika; Sedláčková, Eliška; Hynek, David; Richtera, Lukáš; Adam, Vojtěch (Mendel University in Brno, 2019-12-31)
    The aim of this study was to prepare a sensitive electrochemical biosensor for detection of oncogenic miRNA-21 as a potential biomarker for early detection of cancer. MicroRNAs (miRNAs) are small noncoding RNA, which play ...
  • A simple electrochemical biosensor for the detection of methylated DNA and for methyltransferase activity monitoring 

    Sedláčková, Eliška; Smolíková, Vendula; Birgusová, Eliška; Bytešníková, Zuzana; Richtera, Lukáš; Adam, Vojtěch (Mendel University in Brno, 2019-12-31)
    DNA methylation is one of the well-known epigenetic mechanism which plays a crucial role in the development of various diseases, such as cancer, cardiovascular diseases or diabetes. Electrochemical biosensors promise ...