Synthesis of zinc selenium-based nanoparticles modified by algal oil and their effect on bacterial growth

Abstract

The aim of this study was to develop suitable zinc selenium-based nanoparticles modified by algal oil containing mainly polyunsaturated fatty acids. Dietary omega-6 and omega-3 polyunsaturated fatty acids can affect inflammation reaction of the human body. Polyunsaturated fatty acids include eicosapentaenoic fatty acid and docosahexaenoic fatty acid, which could favourably enhance the correct wound healing. The algal oil would be a great complementary element to accelerate wound healing in combination with nanoparticles. Nowadays, the nanomaterials are beneficial part in different branches, including medicine (e.g. development of new cover materials containing nanoparticles to accelerate the healing effect, targeted drug delivery), cosmetics, textiles, protective equipment, and agriculture. This study includes synthesis of ZnSe nanoparticles modified by algal oil and their characterization by scanning electron microscopy. For the determination of in vitro effect of these nanoparticles on microorganisms, Escherichia coli, Staphylococcus aureus, and methicillinresistant S. aureus were employed. No antibacterial activity was found at these nanoparticles, therefore they could be used as nanocarrier for polyunsaturated fatty acids.