Microfluidic Technology for Clinical Applications of Exosomes

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Date
2019-06-12
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10.3390/mi10060392
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Abstract
Exosomes, a type of nanovesicle, are distinct cellular entities specifically capable of carrying various cargos between cells. It has been hypothesized that exosomes, as an enriched source of biomolecules, may serve as biomarkers for various diseases. This review introduces general aspects of exosomes, presents the challenges in exosome research, discusses the potential of exosomes as biomarkers, and describes the contribution of microfluidic technology to enable their isolation and analysis for diagnostic and disease monitoring. Additionally, clinical applications of exosomes for diagnostic purposes are also summarized.
Keywords
microfluidics, exosomes, clinical applications, extracellular vesicles, cancer, inflammation
Persistent identifier
http://hdl.handle.net/11012/184662
Document type
Peer reviewed
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Final PDF
Source
Micromachines. 2019, vol. 10, issue 6, p. 1-29.
https://www.mdpi.com/2072-666X/10/6/392
DOI
10.3390/mi10060392
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Creative Commons Attribution 4.0 International
Except where otherwise noted, this item's license is described as Creative Commons Attribution 4.0 International