Pokročilé biomateriály
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Antimicrobial Cost-Effective Transparent Hydrogel Films from Renewable Gum Karaya/Chitosan Polysaccharides for Modern Wound Dressings
(American Chemical Society, 2023-04-14)The newest trends in wound healing management and the development of the next generation of dressings are pointing toward natural polymeric materials with important beneficial properties such as antimicrobial effects, ... -
Accelular nanofbrous bilayer scafold intrapenetrated with polydopamine network and implemented into a full-thickness wound of a white-pig model afects infammation and healing process
(BioMed Central, 2023-03-07)Treatment of complete loss of skin thickness requires expensive cellular materials and limited skin grafts used as temporary coverage. This paper presents an acellular bilayer scaffold modified with polydopamine (PDA), ... -
The centrifugal spinning of vitamin doped natural gum fibers for skin regeneration
(Elsevier, 2022-10-15)The study investigates the use of fiber carriers, based on biopolymeric gums as potential candidates for cosmetic and dermatological applications, in particular for skin regeneration. Gum arabic (GA), xanthan gum (XA), and ... -
A New Approach to the Structure-Properties Relationships Determination for Porous Filled Reinforced Materials
(MDPI, 2022-10-18)This study describes a new mathematical approach to the relationship between mechanical properties (tensile modulus, ultimate strength, and strain), composition as well as structure of porous-filled reinforced composites. ... -
Calcined Hydroxyapatite with Collagen I Foam Promotes Human MSC Osteogenic Differentiation
(MDPI, 2022-04-01)Collagen I-based foams were modified with calcined or noncalcined hydroxyapatite or calcium phosphates with various particle sizes and pores to monitor their effect on cell interactions. The resulting scaffolds thus differed ... -
Case Report: Wound Closure Acceleration in a Patient With Toxic Epidermal Necrolysis Using a Lyophilised Amniotic Membrane
(Frontiers Media, 2021-04-16)Background: Toxic epidermal necrolysis (TEN) is a rare life-threatening disease that mainly affects the skin and mucous membranes, resulting from a toxic delayed-type hypersensitivity (DTH) reaction (type IV reaction) to ... -
PLA toughening via bamboo-inspired 3D printed structural design
(Elsevier, 2021-12-01)Bioinspired structures can attain mechanical properties unseen in conventional artificial materials. Specifically, the introduction of a cellular structure with a precisely designed distribution of cells, cell sizes, and ... -
Human Infections by Wohlfahrtiimonas chitiniclastica: A Mini-Review and the First Report of a Burn Wound Infection after Accidental Myiasis in Central Europe
(MDPI, 2021-09-01)Wohlfahrtiimonas chitiniclastica are bacteria that cause rare infections, typically associated with the infestation of an open wound with fly larvae. Here, we present a unique case report of the first W. chitiniclastica ... -
Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation
(MDPI, 2021-06-18)Infectious complications are responsible for the majority of mortalities and morbidities of patients with critical burns. Although bacteria are the predominant etiological agents in such patients, yeasts and fungi have ... -
Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2
(MDPI, 2021-06-25)An experimental animal study was designed to investigate the intervertebral fusion efficiency and safety of a bioresorbable ceramic/biopolymer hybrid implant enriched with FGF2-STAB(R) in comparison with a tricortical bone ... -
Water-born 3Dnanofiber mats usingcost-effectivecentrifugal spinning: comparison with electrospinnig process: A complex study
(WILEY, 2021-02-05)A comparison of the electrostatic and centrifugal spinning of poly(vinyl alcohol) and poly(vinyl pyrrolidone) is shown in terms of the resulting fiber morphology and the process conditions. Specific parameters of centrifugal ... -
Healing and Angiogenic Properties of Collagen/Chitosan Scaffolds Enriched with Hyperstable FGF2-STAB(R) Protein: In Vitro, Ex Ovo and In Vivo Comprehensive Evaluation
(MDPI, 2021-06-01)Wound healing is a process regulated by a complex interaction of multiple growth factors including fibroblast growth factor 2 (FGF2). Although FGF2 appears in several tissue engineered studies, its applications are limited ... -
Mutual influence of selenium nanoparticles and FGF2-STAB® on biocompatible properties of collagen/chitosan 3D scaffolds: in vitro and ex ovo evaluation
(BioMed Central Ltd, 2021-12-01)In a biological system, nanoparticles (NPs) may interact with biomolecules. Specifically, the adsorption of proteins on the nanoparticle surface may influence both the nanoparticles' and proteins' overall bio-reactivity. ... -
The Effect of the Thermosensitive Biodegradable PLGA–PEG–PLGA Copolymer on the Rheological, Structural and Mechanical Properties of Thixotropic Self-Hardening Tricalcium Phosphate Cement
(MDPI, 2019-01-17)The current limitations of calcium phosphate cements (CPCs) used in the field of bone regeneration consist of their brittleness, low injectability, disintegration in body fluids and low biodegradability. Moreover, no method ... -
Femoral bone defect healing using two novel biocompatible degradable materials
(Acta Veterinaria Brno, 2020-05-26)This study was conducted as an in vivo experiment in adult miniature pigs with the aim to test two new biomaterials. An iatrogenic defect was made into the central femoral diaphysis in the experimental animals and subsequently ... -
Lyophilized Polyvinylpyrrolidone Hydrogel for Culture of Human Oral Mucosa Stem Cells
(MDPI, 2021-01-05)This work shows the synthesis of a polyvinylpyrrolidone (PVP) hydrogel by heat-activated polymerization and explores the production of hydrogels with an open porous network by lyophilisation to allow the three-dimensional ... -
Synergistic Effect of Chitosan and Selenium Nanoparticles on Biodegradation and Antibacterial Properties of Collagenous Scaffolds Designed for Infected Burn Wounds
(MDPI, 2020-10-05)A highly porous scaffold is a desirable outcome in the field of tissue engineering. The porous structure mediates water-retaining properties that ensure good nutrient transportation as well as creates a suitable environment ... -
FDM 3D Printed Composites for Bone Tissue Engineering Based on Plasticized Poly(3-hydroxybutyrate)/poly(d,l-lactide) Blends
(MDPI, 2020-11-27)Tissue engineering is a current trend in the regenerative medicine putting pressure on scientists to develop highly functional materials and methods for scaffolds’ preparation. In this paper, the calibrated filaments for ... -
Hybrid Hydrogel Networks by Photocrosslinking of Thermoresponsive alpha,omega-Itaconyl-PLGA-PEG-PLGA Micelles in Water: Influence of the Lithium Phenyl-2,4,6-Trimethylbenzoylphosphinate Photoinitinator
(Wiley-VCH, 2020-08-09)Modification of thermogelling biodegradable copolymers with functional groups enables further covalent crosslinking of physical micelle-based hydrogels formed at specific temperature in water. The resulting hybrid hydrogel ... -
Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing
(MDPI, 2020-06-22)Biodegradable composite nanofibers were electrospun from poly(epsilon-caprolactone) (PCL) and poly(ethylene oxide) (PEO) mixtures dissolved in acetic and formic acids. The variation of PCL:PEO concentration in the polymer ...
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