Now showing items 1-17 of 17

  • Antioxidant status of rats’ blood and liver affected by sodium selenite and selenium nanoparticles 

    Urbánková, Lenka; Horký, Pavel; Skládanka, Jiří; Přibilová, Magdalena; Smolíková, Vendula; Nevrkla, Pavel; Cernei, Natalia Vladimirovna; Lacková, Zuzana; Hedbávný, Josef; Ridošková, Andrea; Adam, Vojtěch; Kopel, Pavel (PeerJ, 2018-05-28)
    Background: Selenium is an essential element; however, at higher doses, it can be toxic. Therefore, alternative nanotechnological solutions are required to overcome toxicological issues, rather than conventional alternatives. ...
  • Behaviour of zinc complexes and zinc sulphide nanoparticles revealed by using screen printed electrodes and spectrometry 

    Nejdl, Lukáš; Ruttkay-Nedecký, Branislav; Kudr, Jiří; Kremplová, Monika; Cernei, Natalia Vladimirovna; Prášek, Jan; Konečná, Marie; Hubálek, Jaromír; Zítka, Ondřej; Kynický, Jindřich; Kopel, Pavel; Kizek, René; Adam, Vojtěch (MDPI AQ, 2013-10-25)
    In this study, we focused on microfluidic electrochemical analysis of zinc complexes (Zn(phen)(his)Cl-2, Zn(his)Cl-2) and ZnS quantum dots (QDs) using printed electrodes. This method was chosen due to the simple (easy to ...
  • Determination of Histamine in Silages Using Nanomaghemite Core (-Fe2O3)-Titanium Dioxide Shell Nanoparticles Off-Line Coupled with Ion Exchange Chromatography 

    Cernei, Natalia Vladimirovna; Lacková, Zuzana; Guráň, Roman; Hynek, David; Skládanka, Jiří; Horký, Pavel; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2016-09-12)
    The presence of biogenic amines is a hallmark of degraded food and its products. Herein, we focused on the utilization of magnetic nanoparticles off-line coupled with ion exchange chromatography with post-column ninhydrin ...
  • Determination of hydroxyproline using ion-exchange liquid chromatography with vis detector and high performance liquid chromatography with fluorescence detector 

    Lacková, Zuzana; Cernei, Natalia Vladimirovna; Štěrbová, Dagmar; Haddad, Yazan Abdulmajeed Eyadh; Rozíková, Veronika; Komprda, Tomáš; Zítka, Ondřej (Mendel University in Brno, 2017-12-31)
    The first aim of the experiment was an optimization of the method for determination of hydroxyproline in a pig skin using high-performance liquid chromatography with fluorescence detector (HPLC-FLD) and ion-exchange liquid ...
  • Differences in Urinary Amino Acid Patterns in Individuals with Different Types of Urological Tumor Urinary Amino Acid Patterns as Markers of Urological Tumors 

    Dušková, Kateřina; Veselý, Štěpán; Do Carmo Silva, Joana Isabel; Cernei, Natalia Vladimirovna; Zítka, Ondřej; Heger, Zbyněk; Adam, Vojtěch; Havlová, Klára; Babjuk, Marek (The International Institute of Anticancer Research, 2018-04-01)
    Background: Insufficient specificity and invasiveness of currently used diagnostic methods raises the need for new markers of urological tumors. The aim of this study was to find a link between the urinary excretion of ...
  • Exposure to 17 beta-Oestradiol Induces Oxidative Stress in the Non-Oestrogen Receptor Invertebrate Species Eisenia fetida 

    Heger, Zbyněk; Michálek, Petr; Guráň, Roman; Havelková, Barbora; Komínková, Markéta; Cernei, Natalia Vladimirovna; Richtera, Lukáš; Beklová, Miroslava; Adam, Vojtěch; Kizek, René (PLOS, 2015-12-22)
    Background The environmental impacts of various substances on all levels of organisms are under investigation. Among these substances, endocrine-disrupting compounds (EDCs) present a threat, although the environmental ...
  • Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer 

    Heger, Zbyněk; Gumulec, Jaromír; Ondrák, Aleš; Škoda, Jan; Zítka, Zdeněk; Cernei, Natalia Vladimirovna; Masařík, Michal; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2016-03-17)
    Herein, we present a study focused on the determination of the influence of long-distance (53 km) bicycle riding on levels of chosen biochemical urinary and serum prostate cancer (PCa) biomarkers total prostate-specific ...
  • Ion exchange chromatography and mass spectrometric methods for analysis of cadmium-phytochelatin (II) complexes 

    Merlos Rodrigo, Miguel Ángel; Cernei, Natalia Vladimirovna; Komínková, Markéta; Zítka, Ondřej; Beklová, Miroslava; Zehnálek, Josef; Kizek, René; Adam, Vojtěch (MDPI, 2013-03-28)
    In this study, in vitro formed Cd-phytochelatin (PC2) complexes were characterized using ion exchange chromatography (IEC) and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. The ...
  • Mathematical evaluation of the amino acid and polyphenol content and antioxidant activities of fruits from different apricot cultivars 

    Sochor, Jiří; Škutková, Helena; Babula, Petr; Zítka, Ondřej; Cernei, Natalia Vladimirovna; Rop, Otakar; Krška, Boris; Adam, Vojtěch; Provazník, Ivo; Kizek, René (MDPI, 2011-09-01)
    Functional foods are of interest because of their significant effects on human health, which can be connected with the presence of some biologically important compounds. In this study, we carried out complex analysis of ...
  • Nanoparticles Suitable for BCAA Isolation Can Serve for Use in Magnetic Lipoplex-Based Delivery System for L, I, V, or R-rich Antimicrobial Peptides 

    Veselý, Radek; Jelínková, Pavlína; Hegerová, Dagmar; Cernei, Natalia Vladimirovna; Kopel, Pavel; Moulick, Amitava; Richtera, Lukáš; Heger, Zbyněk; Adam, Vojtěch; Zítka, Ondřej (MDPI, 2016-04-01)
    This paper investigates the synthesis of paramagnetic nanoparticles, which are able to bind branched chain amino acids (BCAAs)—leucine, valine, and isoleucine and, thus, serve as a tool for their isolation. Further, by ...
  • A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Kudr, Jiří; Gumulec, Jaromír; Blažková, Iva; Zítka, Ondřej; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch; Kizek, René (MDPI, 2013-11-01)
    Doxorubicin is a commonly used antineoplastic agent in the treatment of many types of cancer. Little is known about the interactions of doxorubicin with cardiac biomolecules. Serious cardiotoxicity including dilated ...
  • Papillomavirus infection of roe deer in the Czech Republic and fibropapilloma-associated levels of metallothionein, zinc, and oxidative stress 

    Král, Jiří; Banďouchová, Hana; Brichta, Jiří; Kovacova, Veronika; Ondráček, Karel; Osičková, Jitka; Hrubá, Hana; Hutařová, Zdeňka; Komínková, Markéta; Cernei, Natalia Vladimirovna; Konečná, Marie; Tmejová, Kateřina; Zítka, Ondřej; Adam, Vojtěch; Kízek, René; Skoric, Misa; Tremlová, Bohuslava; Treml, František; Pikula, Jiří (University of Veterinary and Pharmaceutical Sciences, 2015-06-01)
    The present study aimed at the aetiological diagnosis of skin tumours of roe deer (Capreolus capreolus) in the Czech Republic. A total of 33 roe deer specimens showing skin masses were sampled for histopathology, virus ...
  • Paramagnetic Nanoparticles as a Platform for FRET-Based Sarcosine Picomolar Detection 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Křížková, Soňa; Masařík, Michal; Kopel, Pavel; Hodek, Petr; Zítka, Ondřej; Adam, Vojtěch; Kizek, René (Nature Publishing Group, 2015-03-09)
    Herein, we describe an ultrasensitive specific biosensing system for detection of sarcosine as a potential biomarker of prostate carcinoma based on Forster resonance energy transfer (FRET). The FRET biosensor employs ...
  • Sarcosine as a potential prostate cancer biomarker – A review 

    Cernei, Natalia Vladimirovna; Heger, Zbyněk; Gumulec, Jaromír; Zítka, Ondřej; Masařík, Michal; Babula, Petr; Eckschlager, Tomáš; Stiborová, Marie; Kizek, René; Adam, Vojtěch (MDPI, 2013-07-04)
    Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that ...
  • Study of Linkage between Glutathione Pathway and the Antibiotic Resistance of Escherichia coli from Patients Swab 

    Komínková, Markéta; Michálek, Petr; Číhalová, Kristýna; Guráň, Roman; Cernei, Natalia Vladimirovna; Nejdl, Lukáš; Šmerková, Kristýna; Dostálová, Simona; Hegerová, Dagmar; Heger, Zbyněk; Veselý, Radek; Gumulec, Jaromír; Kynický, Jindřich; Xhaxhiu, Kledi; Zítka, Ondřej; Adam, Vojtěch; Kizek, René (MDPI, 2015-03-31)
    In this work, we focused on the differences between bacterial cultures of E. coli obtained from swabs of infectious wounds of patients compared to laboratory E. coli. In addition, blocking of the protein responsible for ...
  • Study of Linkage between Glutathione Pathway and the Antibiotic Resistance of Escherichia coli from Patients’ Swabs 

    Komínková, Markéta; Kizek, René; Michálek, Petr; Číhalová, Kristýna; Guráň, Roman; Cernei, Natalia Vladimirovna; Nejdl, Lukáš; Šmerková, Kristýna; Dostálová, Simona; chudobova, Dagmar; Heger, Zbyněk; Veselý, Radek; Gumulec, Jaromír; Kynický, Jindřich; Xhaxhiu, Kledi; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2015-05-31)
    In this work, we focused on the differences between bacterial cultures of E. coli obtained from swabs of infectious wounds of patients compared to laboratory E. coli. In addition, blocking of the protein responsible for ...
  • Zinc phosphate-based nanoparticles as a novel antibacterial agent: in vivo study on rats after dietary exposure 

    Horký, Pavel; Skaličková, Sylvie; Urbánková, Lenka; Baholet, Daria; Kočiová, Silvia; Býtešníková, Zuzana; Kabourková, Eliška; Lacková, Zuzana; Cernei, Natalia Vladimirovna; Gagić, Milica; Milosavljević, Vedran; Smolíková, Vendula; Václavková, Eva; Nevrkla, Pavel; Knot, Pavel; Kryštofová, Olga; Hynek, David; Kopel, Pavel; Skládanka, Jiří; Adam, Vojtěch; Šmerková, Kristýna (BioMed Central, 2019-02-12)
    Background: Development of new nanomaterials that inhibit or kill bacteria is an important and timely research topic. For example, financial losses due to infectious diseases, such as diarrhea, are a major concern in ...