Now showing items 1-3 of 3

  • Analyses of viral genomes for G-quadruplex forming sequences reveal their correlation with the type of infection 

    Bohálová, Natália; Cantara, Alessio; Bartas, Martin; Kaura, Patrik; Šťastný, Jiří; Pečinka, Petr; Fojta, Miroslav; Mergny, Jean-Louis; Brázda, Václav (Elsevier, 2021-07-01)
    G-quadruplexes contribute to the regulation of key molecular processes. Their utilization for antiviral therapy is an emerging field of contemporary research. Here we present comprehensive analyses of the presence and ...
  • G-quadruplexes in H1N1 influenza genomes 

    Brázda, Václav; Porubiaková, Otília; Cantara, Alessio; Bohálová, Natália; Coufal, Jan; Bartas, Martin; Fojta, Miroslav; Mergny, Jean-Louis (Springer Nature, 2021-01-24)
    Background: Influenza viruses are dangerous pathogens. Seventy-Seven genomes of recently emerged genotype 4 reassortant Eurasian avian-like H1N1 virus (G4-EA-H1N1) are currently available. We investigated the presence and ...
  • Tracing dsDNA Virus–Host Coevolution through Correlation of Their G-Quadruplex-Forming Sequences 

    Bohálová, Natália; Cantara, Alessio; Bartas, Martin; Kaura, Patrik; Šťastný, Jiří; Pečinka, Petr; Fojta, Miroslav; Brázda, Václav (MDPI, 2021-04-01)
    The importance of gene expression regulation in viruses based upon G-quadruplex may point to its potential utilization in therapeutic targeting. Here, we present analyses as to the occurrence of putative G-quadruplex-forming ...