Now showing items 1-4 of 4
Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe-Dnmts axis
(FEBS Press, 2019-05-31)
DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells ...
Investigating the interplay between sarcosine and Ca2+-dependent signaling in prostate cells
(Mendel University in Brno, 2019-01-02)
It has been shown that sarcosine supplementation stimulates proliferation and invassivenes of prostate cells. Nevertheless, the exact molecular mechanism responsible for this phenomenon is not known. In the present study ...
Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma
(Springer Nature, 2018-12-01)
The hypothesis that dogs can detect malignant tumours through the identification of specific molecules is nearly 30 years old. To date, several reports have described the successful detection of distinct types of cancer. ...
Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer
Herein, we present a study focused on the determination of the influence of long-distance (53 km) bicycle riding on levels of chosen biochemical urinary and serum prostate cancer (PCa) biomarkers total prostate-specific ...