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Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma
(Springer Nature, 2018-12-01)
The hypothesis that dogs can detect malignant tumours through the identification of specific molecules is nearly 30 years old. To date, several reports have described the successful detection of distinct types of cancer. ...
The Zinc-Schiff Base-Novicidin Complex as a Potential Prostate Cancer Therapy
(PLOS, 2016-10-11)
Prostate cancer cells control energy metabolism by chelating intracellular zinc. Thus, zinc
delivery has been a popular therapeutic approach for prostate cancer. Here, we propose
the use of the membrane-penetrating peptide ...
Study of Linkage between Glutathione Pathway and the Antibiotic Resistance of Escherichia coli from Patients’ Swabs
(MDPI, 2015-05-31)
In this work, we focused on the differences between bacterial cultures of E. coli obtained from swabs of infectious wounds of patients compared to laboratory E. coli. In addition, blocking of the protein responsible for ...
Anticancerogenic effect of spices due to phenolic and flavonoid compounds – in vitro evaluation on prostate cells
(MDPI, 2017-09-28)
This study shows the effects of spices, and their phenolic and flavonoid compounds, on prostate cell lines (PNT1A, 22RV1 and PC3). The results of an MTT assay on extracts from eight spices revealed the strongest inhibitory ...
Flow Injection Analysis with Electrochemical Detection for Rapid Identification of Platinum-Based Cytostatics and Platinum Chlorides in Water
(MDPI, 2014-02-04)
Platinum-based cytostatics, such as cisplatin, carboplatin or oxaliplatin are widely used agents in the treatment of various types of tumors. Large amounts of these
drugs are excreted through the urine of patients into ...
Apoferritin as an ubiquitous nanocarrier with excellent shelf life
(Dove Media Press, 2017-03-24)
Due to many adverse effects of conventional chemotherapy, novel methods of targeting drugs to cancer cells are being investigated. Nanosize carriers are a suitable platform for this specific delivery. Herein, we evaluated ...
Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer
(MDPI, 2016-03-17)
Herein, we present a study focused on the determination of the influence of long-distance
(53 km) bicycle riding on levels of chosen biochemical urinary and serum prostate cancer (PCa)
biomarkers total prostate-specific ...
Paramagnetic Nanoparticles as a Platform for FRET-Based Sarcosine Picomolar Detection
(Nature Publishing Group, 2015-03-09)
Herein, we describe an ultrasensitive specific biosensing system for detection of sarcosine as a potential
biomarker of prostate carcinoma based on Forster resonance energy transfer (FRET). The FRET biosensor
employs ...
Targeting Neuroblastoma Cell Surface Proteins: Recommendations for Homology Modeling of hNET, ALK, and TrkB
(Frontiers, 2017-01-20)
Targeted therapy is a promising approach for treatment of neuroblastoma as evident
from the large number of targeting agents employed in clinical practice today. In
the absence of known crystal structures, researchers rely ...
Magnetic nanoparticles: From Design and Synthesis to Real World Applications
(MDPI, 2017-09-01)
The increasing number of scientific publications focusing on magnetic materials indicates growing interest in the broader scientific community. Substantial progress was made in the synthesis of magnetic materials of desired ...