Now showing items 1-5 of 5
Determination of Critical Parameters of Drug Substance Influencing Dissolution: A Case Study
(Hindawi Publishing Corporation, 2014-09-15)
The purpose of this study was to specify critical parameters (physicochemical characteristics) of drug substance that can affect dissolution profile/dissolution rate of the final drug product manufactured by validated ...
Macroscopic derivation of the kinetic mass-action law
Using several reaction examples with experimentally determined rate equations, traditional mass action rate equations are shown to be simplified forms of polynomial approximation to a general rate function derived by ...
Fluorescence study of freeze-drying as a method for support the interactions between hyaluronan and hydrophobic species
A freeze-drying method enabling solubilization of hydrophobic species in aqueous solutions of native hyaluronan is described. The method is based on opening the access to supposed hydrophobic patches on hyaluronan by ...
Thermodynamic analysis of chemically reacting mixtures – comparison of first and second order models
Recently, a method based on non-equilibrium continuum thermodynamics which derives thermodynamically consistent reaction rate models together with thermodynamic constraints on their parameters was analyzed using a triangular ...
Production of Polyhydroxyalkanoates Using Hydrolyzates of Spruce Sawdust: Comparison of Hydrolyzates Detoxification by Application of Overliming, Active Carbon, and Lignite
(MDPI AG, 2017-05-28)
Polyhydroxyalkanoates (PHAs) are bacterial polyesters which are considered biodegradable alternatives to petrochemical plastics. PHAs have a wide range of potential applications, however, the production cost of this ...