Monitoring The Parameters Of Cells Migrating In Pseudo-3d Extracellular Matrix
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Cell migration plays an essential role in a number of biological processes, such as embryogenesis,the immune response, wound healing and inflammation. Most research regarding cellmigration is based on experiments using two-dimensional (2D) cell cultures, and the detailed molecularand biophysical mechanisms of these processes are already well known. However, muchless is known about cell behaviour in the three-dimensional (3D) environment of living tissues.Pseudo-three-dimensional (pseudo-3D) cell cultures bridge the gap between 2D and 3D geometriesand combine their advantages. This review presents the quantitative evaluation of human mesenchymalstem cells (hMSCs) migration parameters in pseudo-3D artificial extracellular matrix(ECM) of various compositions.
Document typePeer reviewed
Document versionFinal PDF
SourceProceedings I of the 27st Conference STUDENT EEICT 2021: General papers. s. 306-310. ISBN 978-80-214-5942-7
- Student EEICT 2021