Now showing items 1-4 of 4

  • Cisplatin enhances cell stiffness and decreases invasiveness rate in prostate cancer cells by actin accumulation 

    Raudenská, Martina; Kratochvílová, Monika; Vičar, Tomáš; Gumulec, Jaromír; Balvan, Jan; Polanská, Hana; Přibyl, Jan; Masařík, Michal (NATURE PUBLISHING GROUP, 2019-02-07)
    We focused on the biomechanical and morphological characteristics of prostate cancer cells and their changes resulting from the effect of docetaxel, cisplatin, and long-term zinc supplementation. Cell population surviving ...
  • The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease 

    Roy, Sudeep; Gumulec, Jaromír; Kumar, Akhil; Raudenská, Martina; Baig, Mohd Hassan; Polanská, Hana; Balvan, Jan; Gupta, Mansi; Babula, Petr; Odstrčilík, Jan; Choi, Inho; Provazník, Ivo; Masařík, Michal (Wiley Periodicals, 2017-08-15)
    Metallothioneins (MTs) are a class of ubiquitously occurring low-molecular-weight cysteine- and metal-rich proteins containing sulfur-based metal clusters. MT-3 exhibits neuro-inhibitory activity. The possibility to enhance ...
  • Quantitative Phase Dynamics of Cancer Cell Populations Affected by Blue Light 

    Feith, Marek; Vičar, Tomáš; Gumulec, Jaromír; Raudenská, Martina; Gjörloff Wingren, Anette; Masařík, Michal; Balvan, Jan (MDPI, 2020-04-09)
    Increased exposition to blue light may induce many changes in cell behavior and significantly affect the critical characteristics of cells. Here we show that multimodal holographic microscopy (MHM) within advanced image ...
  • The Quantitative-Phase Dynamics of Apoptosis and Lytic Cell Death 

    Vičar, Tomáš; Raudenská, Martina; Gumulec, Jaromír; Balvan, Jan (Springer Nature, 2020-01-31)
    Cell viability and cytotoxicity assays are highly important for drug screening and cytotoxicity tests of antineoplastic or other therapeutic drugs. Even though biochemical-based tests are very helpful to obtain preliminary ...