Now showing items 208-227 of 262

  • A quantitative analysis of 3D-cell distribution in regenerating muscle-skeletal system with synchrotron X-ray computed microtomography 

    Tesařová, Markéta; Kalasová, Dominika; Zikmund, Tomáš; Novotná, Marie; Kaiser, Jozef (Springer Nature, 2018-09-20)
    One of the greatest enigmas of modern biology is how the geometry of muscular and skeletal structures are created and how their development is controlled during growth and regeneration. Scaling and shaping of vertebrate ...
  • Quantitative phase imaging through scattering media by means of coherence-controlled holographic microscope 

    Kollárová, Věra; Čolláková, Jana; Dostál, Zbyněk; Veselý, Pavel; Chmelík, Radim (SPIE, 2015-11-01)
    A coherence-controlled holographic microscope (CCHM) enables quantitative phase imaging with coherent as well as incoherent illumination. The low spatially coherent light induces a coherence gating effect, which makes ...
  • Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell invasion 

    Tolde, Ondřej; Gandalovičová, Aneta; Křížová, Aneta; Veselý, Pavel; Chmelík, Radim; Rösel, Daniel; Brábek, Jan (Springer Nature, 2018-08-13)
    Observation and analysis of cancer cell behaviour in 3D environment is essential for full understanding of the mechanisms of cancer cell invasion. However, label-free imaging of live cells in 3D conditions is optically ...
  • Raman and XPS studies of ammonia sensitive polypyrrole nanorods and nanoparticles 

    Šetka, Milena; Calavia, Raul; Vojkůvka, Lukáš; Llobet, Eduard; Drbohlavová, Jana; Vallejos Vargas, Stella (Springer Nature, 2019-06-11)
    Raman and XPS studies of ammonia sensitive polypyrrole nanorods and nanoparticles, respectively and tested upon ammonia exposure using Raman and X-ray photonelectrone spectroscopy (XPS). Characterization of both nanomaterilas ...
  • Research Update: Focused ion beam direct writing of magnetic patterns with controlled structural and magnetic properties 

    Urbánek, Michal; Flajšman, Lukáš; Křižáková, Viola; Gloss, Jonáš; Horký, Michal; Schmid, Michael; Varga, Peter (AIP Publishing, 2018-06-01)
    Focused ion beam irradiation of metastable Fe78Ni22 thin films grown on Cu(100) substrates is used to create ferromagnetic, body-centered cubic patterns embedded into paramagnetic, face-centered-cubic surrounding. The ...
  • Resistive switching in TiO2 nanocolumn arrays electrochemically grown 

    Márik, Marian; Mozalev, Alexander; Hubálek, Jaromír; Bendová, Mária (IOP Publishing, 2017-04-21)
    Resistive switching in metal oxides, especially in TiO2, has been intensively investigated for potential application in non-volatile memory microdevices. As one of the working mechanisms, a conducting filament consisting ...
  • Robotic 3D Scanner as an Alternative to Standard Modalities of Medical Imaging 

    Chromý, Adam; Žalud, Luděk (Springer Science and Business Media Deutschland GmbH, 2014-01-06)
    There are special medical cases, where standard medical imaging modalities are able to offer sufficient results, but not in the optimal way. It means, that desired results are produced with unnecessarily high expenses, ...
  • The Role of Metallothionein in Oxidative Stress 

    Ruttkay-Nedecký, Branislav; Nejdl, Lukáš; Gumulec, Jaromír; Zítka, Ondřej; Masařík, Michal; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch; Kizek, René (MDPI, 2013-03-15)
    Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule. They cause the molecule to become highly reactive. The free radicals are also known to play a dual role in ...
  • Ruthenium-based core-shell nanoparticles with exceptional in vitro biocompatibility 

    Buchtelová, Hana; Strmiska, Vladislav; Dostálová, Simona; Michálek, Petr; Křížková, Soňa; Kopel, Pavel; Hynek, David; Richtera, Lukáš; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    The current study demonstrates design preparation and characterization of biocompatible hybrid ruthenium core-shell nanoparticles (RuNPs) coated with polyvinylpyrrolidone (PVP) and polyoxyethylene stearate (POES). The ...
  • Sarcosine as a potential prostate cancer biomarker – A review 

    Cernei, Natalia Vladimirovna; Heger, Zbyněk; Gumulec, Jaromír; Zítka, Ondřej; Masařík, Michal; Babula, Petr; Eckschlager, Tomáš; Stiborová, Marie; Kizek, René; Adam, Vojtěch (MDPI, 2013-07-04)
    Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that ...
  • Sarcosine degradation pathway is involved in the epigenetics of prostate cells 

    Strmiska, Vladislav; Michálek, Petr; Buchtelová, Hana; Lacková, Zuzana; Guráň, Roman; Křížková, Soňa; Pompeiano Vaníčková, Lucie; Zítka, Ondřej; Stiborová, Marie; Eckschlager, Tomáš; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    It has been shown that sarcosine suplementation stimulates the proliferation of prostate cells and also their invassiveness. In present study we show that enzymes conected with sarcosine conversion to glycine (sarcosine ...
  • Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe-Dnmts axis 

    Strmiska, Vladislav; Michálek, Petr; Lacková, Zuzana; Guráň, Roman; Křížková, Soňa; Pompeiano Vaníčková, Lucie; Zítka, Ondřej; Stiborová, Marie; Eckschlager, Tomáš; Klejdus, Bořivoj; Pacík, Dalibor; Tvrdíková, Eliška; Keil, Claudia; Haase, Hajo; Adam, Vojtěch; Heger, Zbyněk (FEBS Press, 2019-05-31)
    DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells ...
  • Sarcosine up-regulates expression of genes involved in cell cycle progression of metastatic models of prostate cancer 

    Heger, Zbyněk; Merlos Rodrigo, Miguel Ángel; Michálek, Petr; Polanská, Hana; Masařík, Michal; Vít, Vítězslav; Plevová, Mariana; Pacík, Dalibor; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch (PLOS, 2016-11-08)
    The effects of sarcosine on the processes driving prostate cancer (PCa) development remain still unclear. Herein, we show that a supplementation of metastatic PCa cells (androgen independent PC-3 and androgen dependent ...
  • Selective Laser Melting Strategy for Fabrication of Thin Struts Usable in Lattice Structures 

    Vrána, Radek; Koutný, Daniel; Paloušek, David; Pantělejev, Libor; Jaroš, Jan; Zikmund, Tomáš; Kaiser, Jozef (MDPI, 2018-09-18)
    This paper deals with the selective laser melting (SLM) processing strategy for strut-lattice structure production which uses only contour lines and allows the porosity and roughness level to be managed based on ombination ...
  • Selectively arranged single-wire based nanosensor array systems for gas monitoring 

    Chmela, Ondřej; Sadílek, Jakub; Somer, Jakub; Mohan, Rajneesh; Hubálek, Jaromír; Vallejos Vargas, Stella (Royal Society of Chemistry, 2018-05-01)
    Gas nanosensors, comprised of arrays of nanoelectrodes with finger-widths of ~100 nm developed by electron beam lithography and aerosol assisted chemical vapor deposited non-functionalized and Pt-functionalized tungsten ...
  • Self-Ordered TiO2 Quantum Dot Array Prepared via Anodic Oxidation 

    Drbohlavová, Jana; Hrdý, Radim; Salyk, Ota; Kizek, René; Hubálek, Jaromír (SpringerOpen, 2012-02-14)
    The paper brings the important information about synthesis of titania quantum dots in the form of sensor array which is suitable for various biomolecules (DNA, proteins) sensing in vitro. The usage of this fluorescence ...
  • Sensitive biosensor for detection oncogenic miRNA-21 

    Vaňová, Veronika; Sedláčková, Eliška; Hynek, David; Richtera, Lukáš; Adam, Vojtěch (Mendel University in Brno, 2019-12-31)
    The aim of this study was to prepare a sensitive electrochemical biosensor for detection of oncogenic miRNA-21 as a potential biomarker for early detection of cancer. MicroRNAs (miRNAs) are small noncoding RNA, which play ...
  • Serum and Tissue Zinc in Epithelial Malignancies: A Meta-Analysis 

    Gumulec, Jaromír; Masařík, Michal; Adam, Vojtěch; Eckschlager, Tomáš; Provazník, Ivo; Kizek, René (PLOS, 2014-06-19)
    Background and Objectives: Current studies give us inconsistent results regarding the association of neoplasms and zinc(II) serum and tissues concentrations. The results of to-date studies using meta-analysis are summarized ...
  • Serum metallothioneins in childhood tumours – A potential prognostic marker 

    Kruseová, Jarmila; Hynek, David; Adam, Vojtěch; Kizek, René; Průša, Richard; Hraběta, Jan; Eckschlager, Tomáš (MDPI, 2013-06-06)
    Metallothioneins (MT) are low molecular weight, cysteine-rich proteins maintaining metal ions homeostasis. They play a role in carcinogenesis and may also cause chemoresistance. The aim of the study was to explore the ...
  • Sharka: The Past, The Present and The Future 

    Sochor, Jiří; Babula, Petr; Adam, Vojtěch; Krška, Boris; Kizek, René (MDPI, 2012-11-01)
    Members the Potyviridae family belong to a group of plant viruses that are causing devastating plant diseases with a significant impact on agronomy and economics. Plum pox virus (PPV), as a causative agent of sharka disease, ...