Now showing items 221-239 of 239

  • Targeting Neuroblastoma Cell Surface Proteins: Recommendations for Homology Modeling of hNET, ALK, and TrkB 

    Haddad, Yazan Abdulmajeed Eyadh; Heger, Zbyněk; Adam, Vojtěch (Frontiers, 2017-01-20)
    Targeted therapy is a promising approach for treatment of neuroblastoma as evident from the large number of targeting agents employed in clinical practice today. In the absence of known crystal structures, researchers rely ...
  • Time-dependent growth of silica shells on CdTe quantum dots 

    Modlitbová, Pavlína; Klepárník, Karel; Farka, Zdeněk; Pořízka, Pavel; Skládal, Petr; Novotný, Karel; Kaiser, Jozef (MDPI, 2018-06-16)
    The purpose of this study is to investigate the time dependent growth of silica shell on CdTe quantum dots to get its optimum thickness for applications in practice. The core/shell structured silica-coated CdTe quantum ...
  • Towards Automatic UAS-Based Snow-Field Monitoring for Microclimate Research 

    Gábrlík, Petr; Janata, Přemysl; Žalud, Luděk; Harčarik, Josef (MDPI, 2019-04-25)
    This article presents unmanned aerial system (UAS)-based photogrammetry as an efficient method for the estimation of snow-field parameters, including snow depth, volume, and~snow-covered area. Unlike~similar studies employing ...
  • Transcriptomic landscape of cisplatin-resistant neuroblastoma cells 

    Merlos Rodrigo, Miguel Ángel; Buchtelová, Hana; Jimenez Jimenez, Ana Maria; Adam, Pavlína; Babula, Petr; Heger, Zbyněk; Adam, Vojtěch (MDPI, 2019-03-31)
    The efficiency of cisplatin (CDDP) is significantly hindered by the development of resistance during the treatment course. To gain a detailed understanding of the molecular mechanisms underlying the development of cisplatin ...
  • Tricalcium Phosphate - Magnesium Interface: Microstructure and Properties 

    Casas Luna, Mariano; Montufar Jimenez, Edgar Benjamin; Horynová, Miroslava; Gejdoš, Pavel; Klakurková, Lenka; Díaz de la Torre, Sebastian; Kaiser, Jozef; Čelko, Ladislav (Trans Tech Publications, 2017-01-01)
    The fabrication of a composite material based on magnesium (Mg) and tricalcium phosphate is reported in this work. Rods of -tricalcium phosphate (-TCP) were processed and consolidated together with pure Mg powder through ...
  • Trithiocyanurate Complexes of Iron, Manganese and Nickel and Their Anticholinesterase Activity 

    Kopel, Pavel; Doležal, Karel; Langer, Vratislav; Jun, Daniel; Adam, Vojtěch; Kuča, Kamil; Kizek, René (MDPI, 2014-04-08)
    The complexes of Fe(II), Mn(II) and Ni(II) with a combination of a Schiff base, nitrogen-donor ligand or macrocyclic ligand and trithiocyanuric acid (ttcH3) were prepared and characterized by elemental analysis and ...
  • Trk receptors and neurotrophins cross-interactions: New perspective to manipulating therapeutic side-effects 

    Haddad, Yazan Abdulmajeed Eyadh; Adam, Vojtěch; Heger, Zbyněk (Frontiers, 2017-05-03)
    Some therapeutic side-effects result from simultaneous activation of homolog receptors by the same ligand. Tropomyosin receptor kinases (TrkA, TrkB and TrkC) play a major role in the development and biology of neurons ...
  • Use of micro computed-tomography and 3D printing for reverse engineering of mouse embryo nasal capsule 

    Tesařová, Markéta; Zikmund, Tomáš; Kaucká, Markéta; Adameyko, Igor; Jaroš, Josef; Paloušek, David; Škaroupka, David; Kaiser, Jozef (IOP Publishing, 2016-03-02)
    Imaging of increasingly complex cartilage in vertebrate embryos is one of the key tasks of developmental biology. This is especially important to study shape-organizing processes during initial skeletal formation and growth. ...
  • Use of the industrial X-ray computed microtomography to address scientific questions in developmental biology 

    Tesařová, Markéta; Zikmund, Tomáš; Kaiser, Jozef (NDT.net, 2019-03-01)
    X-ray computed microtomography (microCT) that allows to extract quantitative 3D information about various objects is already a well-established and widely used industrial technique for non-destructive testing, materials ...
  • Utility of several microsatellite markers for the genetic characterisation of three ex situ populations of threatened caprine taxa (Capra aegagrus, C. cylindricornis and C. falconeri) 

    Štohl, Radek (ARCHIV FUR TIERZUCHT, 2015-10-07)
    Caprines belong to the most endangered group of mammals and artiodactyls suffering from many negative human impacts. Fortunately, many of them are protected and managed by national and international legislation and in situ ...
  • Utilization of antibody-nanoparticle conjugates as a tool for immunochemistry with ICP-MS detection 

    Vlčnovská, Marcela; Tvrdoňová, Michaela; Vaculovičová, Markéta; Vaculovič, Tomáš (Mendel University in Brno, 2019-01-02)
    Immunoanalytical techniques are key methods of application in clinical diagnostics, genomics, proteomics and other biochemical and molecular biology disciplines. Most often, they are based on the ability of labeled antibodies ...
  • Verification of Nine-phase PMSM Model in d-q Coordinates with Mutual Couplings 

    Kozovský, Matúš; Blaha, Petr; Václavek, Pavel (IEEE, 2016-11-25)
    Electric motors with more than three phases have many advantages comparing to ordinary three-phase motor. For this reason it is natural to pay attention to hem and to work on advanced control methods. Control algorithms ...
  • Voltammetry as a Tool for Characterization of CdTe Quantum Dots 

    Adam, Pavlína; Vaculovičová, Markéta; Hubálek, Jaromír; Adam, Vojtěch; Kizek, René (MDPI, 2013-06-27)
    Electrochemical detection of quantum dots (QDs) has already been used in numerous applications. However, QDs have not been well characterized using voltammetry, with respect to their characterization and quantification. ...
  • Water-dispersible TiO2 nanoparticles via a biphasic solvothermal reaction method 

    Mohan, Rajneesh; Drbohlavová, Jana; Hubálek, Jaromír (Springer, 2013-12-01)
    A biphasic solvothermal reaction method has been used for the synthesis of TiO2 nanoparticles (NPs). In this method, hydrolysis and nucleation occur at the interface of organic phase (titanium (IV) n-propoxide and stearic acid ...
  • X-ray induced electrostatic graphene doping via defect charging in gate dielectric 

    Procházka, Pavel; Mareček, David; Lišková, Zuzana; Čechal, Jan; Šikola, Tomáš (NPG, 2017-04-03)
    Graphene field effect transistors are becoming an integral part of advanced devices. Hence, the advanced strategies for both characterization and tuning of graphene properties are required. Here we show that the X-ray ...
  • Zinc phosphate nanoparticles as an antimicrobial agent and their impact on rats microbiota 

    Kočiová, Silvia; Bytešníková, Zuzana; Horký, Pavel; Kopel, Pavel; Adam, Vojtěch; Šmerková, Kristýna (Mendel University in Brno, 2019-01-02)
    Nano minerals, especially trace minerals, are widely used in different fields, but mostly in animal systems. They can improve overall immunity and also a digestive efficacy in livestock. In this case, nanometals as nano ...
  • Zinc Phosphate Nanoparticles Preparation and Their Antimicrobial Activity 

    Kopel, Pavel; Cernei, Natalia Vladimirovna; Gagić, Milica; Horký, Pavel; Šmerková, Kristýna; Adam, Vojtěch (Tanger, 2019-02-01)
    Zinc phosphate particles were prepared by reaction of zinc nitrate with hydrogen phosphate, diphosphate and triphosphate, and characterized by Dynamic Light scattering (DLS) and Scanning Electron Microscopy (SEM). Antibacterial ...
  • Zinc phosphate-based nanoparticles as a novel antibacterial agent: in vivo study on rats after dietary exposure 

    Horký, Pavel; Skaličková, Sylvie; Urbánková, Lenka; Baholet, Daria; Kočiová, Silvia; Bytešníková, Zuzana; Kabourková, Eliška; Lacková, Zuzana; Cernei, Natalia Vladimirovna; Gagić, Milica; Milosavljević, Vedran; Smolíková, Vendula; Václavková, Eva; Nevrkla, Pavel; Knot, Pavel; Kryštofová, Olga; Hynek, David; Kopel, Pavel; Skládanka, Jiří; Adam, Vojtěch; Šmerková, Kristýna (BioMed Central, 2019-02-12)
    Background: Development of new nanomaterials that inhibit or kill bacteria is an important and timely research topic. For example, financial losses due to infectious diseases, such as diarrhea, are a major concern in ...
  • The Zinc-Schiff Base-Novicidin Complex as a Potential Prostate Cancer Therapy 

    Milosavljević, Vedran; Haddad, Yazan Abdulmajeed Eyadh; Merlos Rodrigo, Miguel Ángel; Moulick, Amitava; Polanská, Hana; Hynek, David; Heger, Zbyněk; Kopel, Pavel; Adam, Vojtěch (PLOS, 2016-10-11)
    Prostate cancer cells control energy metabolism by chelating intracellular zinc. Thus, zinc delivery has been a popular therapeutic approach for prostate cancer. Here, we propose the use of the membrane-penetrating peptide ...