Now showing items 1-20 of 236

  • A 3D Microfluidic Chip for Electrochemical Detection of Hydrolysed Nucleic Bases by a Modified Glassy Carbon Electrode 

    Vlachová, Jana; Tmejová, Kateřina; Kopel, Pavel; Korabík, Michal; Zítka, Jan; Hynek, David; Kynický, Jindřich; Adam, Vojtěch; Kizek, René (MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, 2015-02-01)
    Modification of carbon materials, especially graphene-based materials, has wide applications in electrochemical detection such as electrochemical lab-on-chip devices. A glassy carbon electrode (GCE) modified with chemically ...
  • An Acetylcholinesterase-Based Chronoamperometric Biosensor for Fast and Reliable Assay of Nerve Agents 

    Pohanka, Miroslav; Adam, Vojtěch; Kizek, René (MDPI, 2013-09-01)
    The enzyme acetylcholinesterase (AChE) is an important part of cholinergic nervous system, where it stops neurotransmission by hydrolysis of the neurotransmitter acetylcholine. It is sensitive to inhibition by organophosphate ...
  • Acheson, Silicon Carbide, and the Electric Arc 

    Vanýsek, Petr (The Electrochemical Society, 2017-03-15)
    This historical article looks at the technological discovery of Edward Goodrich Acheson of silicon carbide as one of the number of technological discoveries of the end of 19th century based on the use of electricity and ...
  • The adhesion of normal human dermal fibroblasts to the cyclopropylamine plasma polymers studied by holographic microscopy 

    Štrbková, Lenka; Manakhov, Anton; Zajíčková, Lenka; Stoica, Adrian; Veselý, Pavel; Chmelík, Radim (Elsevier B.V., 2016-06-15)
    The understanding of cell–surface interactions plays an important role for the biomaterials development and bioengineering. Although it is already known that amine groups increase the cell adhesion and proliferation, the ...
  • Advantages of Combined Sintering Compared to Conventional Sintering of Mechanically Activated Magnesium Titanate 

    Filipović, Suzana; Obradović, Nina; Pavlović, Vladimir B.; Kosanović, Darko; Mitrić, Miodrag; Mitrović, Nebojsa; Pouchlý, Václav; Kachlík, Martin; Maca, Karel (International Institute for the Science of Sintering, Beograd, 2014-09-01)
    In this article, the advantages of combined sintering in comparison with the conventional one, of mechanically activated magnesium titanate ceramic were investigated. The stoichiometric mixtures of MgO and TiO2 were ...
  • Algal Biomass Analysis by Laser-Based Analytical Techniques - A Review 

    Pořízka, Pavel; Prochazková, Petra; Prochazka, David; Sládková, Lucia; Novotný, Jan; Petrilak, Michal; Brada, Michal; Samek, Ota; Pilát, Zdeněk; Zemánek, Pavel; Adam, Vojtěch; Kizek, René; Novotný, Karel; Kaiser, Jozef (MDPI AG, 2014-09-23)
    Algal biomass that is represented mainly by commercially grown algal strains has recently found many potential applications in various fields of interest. Its utilization has been found advantageous in the fields of ...
  • Amalgam electrode-based electrochemical detector for on-site direct determination of cadmium(II) and lead(II) from soils 

    Nejdl, Lukáš; Kynický, Jindřich; Brtnický, Martin; Vaculovičová, Markéta; Adam, Vojtěch (MDPI, 2017-08-01)
    Toxic metal contamination of the environment is a global issue. In this paper, we present a low-cost and rapid production of amalgam electrodes used for determination of Cd(II) and Pb(II) in environmental samples (soils ...
  • Analysis of neural crest-derived clones reveals novel aspects of facial development 

    Kaiser, Jozef; Zikmund, Tomáš; Tesařová, Markéta (American Association for the Advancement of Science (AAAS), 2016-08-03)
    Cranial neural crest cells populate the future facial region and produce ectomesenchyme-derived tissues, such as cartilage, bone, dermis, smooth muscle, adipocytes, and many others. However, the contribution of individual ...
  • Anticancerogenic effect of spices due to phenolic and flavonoid compounds – in vitro evaluation on prostate cells 

    Lacková, Zuzana; Buchtelová, Hana; Buchtová, Žaneta; Klejdus, Bořivoj; Heger, Zbyněk; Brtnický, Martin; Kynický, Jindřich; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2017-09-28)
    This study shows the effects of spices, and their phenolic and flavonoid compounds, on prostate cell lines (PNT1A, 22RV1 and PC3). The results of an MTT assay on extracts from eight spices revealed the strongest inhibitory ...
  • Antimicrobial activity of CdTe QDs modified with lanthanides on pseudomonas aeruginosa 

    Jelínková, Pavlína; Koudelková, Zuzana; Kopel, Pavel; Moulick, Amitava; Adam, Vojtěch (Mendel University in Brno, 2017-12-31)
    The aim of this study is to obtain data based on an experimental procedure and check the effectiveness of some antibacterial agents against pathogenic bacteria. In the present experiment, two different nanoparticles (Cadmium ...
  • Antioxidant activity of yoghurt supplemented with natural additives 

    Ananbeh, Hanadi Abd Al Rahman Ali; Voběrková, Stanislava; Kumbár, Vojtěch (Mendel University in Brno, 2017-12-31)
    The aims of this study were the estimation of difference in physiochemical properties and antioxidant activity of yoghurts supplemented by different natural additives. In addition, the changes in physiochemical properties ...
  • Antioxidant response of arabidopsis thaliana to ZnSe-nanoparticles, selenium and zinc ions 

    Koláčková, Martina; Moulick, Amitava; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    The impact of zinc selenide nanoparticles (ZnSe-NPs) on plants is still unknown. The intention of this work was to compare phytotoxicity of ZnSe-NPs and selenium and zinc ions in 100, 250 and 500 M concentrations. Young ...
  • Antioxidant status of rats’ blood and liver affected by sodium selenite and selenium nanoparticles 

    Urbánková, Lenka; Horký, Pavel; Skládanka, Jiří; Přibilová, Magdalena; Smolíková, Vendula; Nevrkla, Pavel; Cernei, Natalia Vladimirovna; Lacková, Zuzana; Hedbávný, Josef; Ridošková, Andrea; Adam, Vojtěch; Kopel, Pavel (PeerJ, 2018-05-28)
    Background: Selenium is an essential element; however, at higher doses, it can be toxic. Therefore, alternative nanotechnological solutions are required to overcome toxicological issues, rather than conventional alternatives. ...
  • Apoferritin as an ubiquitous nanocarrier with excellent shelf life 

    Dostálová, Simona; Vašíčková, Kateřina; Hynek, David; Křížková, Soňa; Richtera, Lukáš; Vaculovičová, Markéta; Eckschlager, Tomáš; Stiborová, Marie; Heger, Zbyněk; Adam, Vojtěch (Dove Media Press, 2017-03-24)
    Due to many adverse effects of conventional chemotherapy, novel methods of targeting drugs to cancer cells are being investigated. Nanosize carriers are a suitable platform for this specific delivery. Herein, we evaluated ...
  • Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery 

    Blažková, Iva; Nguyen, Hoai Viet; Dostálová, Simona; Kopel, Pavel; Stanisavljevic, Maja; Vaculovičová, Markéta; Stiborová, Marie; Eckschlager, Tomáš; Kizek, René; Adam, Vojtěch (MDPI, 2013-06-27)
    Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation ...
  • Apoferritin-mediated doxorubicin internalization through transferrin receptor 1 

    Krausová, Kateřina; Dostálová, Simona; Hynek, David; Křížková, Soňa; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    This work is aimed at the possibilities of targeted drug delivery into the tumour tissue. This approach can greatly reduce the otherwise serious side effects of conventional treatment - systemic toxicity. For this purpose, ...
  • The application of capillary electrophoresis, mass spectrometry and Brdicka reaction in human and rabbit metallothioneins analysis 

    Kepinska, Marta; Křížková, Soňa; Guszpit, Ewelina; Merlos Rodrigo, Miguel Ángel; Milnerowicz, Halina (Wroclaw Medical University, 2018-11-30)
    Background. Metallothioneins (MTs) constitute a family of evolutionary conserved low molecular weight proteins with small variations in their amino acid sequences. They play a role in the regulation of trace metals metabolism, ...
  • Application of the Enzymatic Electrochemical Biosensors for Monitoring Non-Competitive Inhibition of Enzyme Activity by Heavy Metals 

    Amirmansoor, Ashrafi; Sýs, Milan; Sedláčková, Eliška; Farag, Amir Shaaban; Adam, Vojtěch; Přibyl, Jan; Richtera, Lukáš (MDPI, 2019-07-03)
    The inhibition effect of the selected heavy metals (Ag+, Cd2+, Cu2+, and Hg2+) on glucose oxidase (GOx) enzyme from Aspergillus niger (EC 1.1.3.4.) was studied using a new amperometric biosensor with an electrochemical ...
  • Are Early Somatic Embryos of the Norway Spruce (Picea abies (L.) Karst.) Organised? 

    Petřek, Jiří; Zítka, Ondřej; Adam, Vojtěch; Bartušek, Karel; Anjum, Naser A.; Pereira, Eduarda; Havel, Ladislav; Kizek, René (PLOS, 2015-12-01)
    Somatic embryogenesis in conifer species has great potential for the forestry industry. Hence, a number of methods have been developed for their efficient and rapid propagation through somatic embryogenesis. Although ...
  • Automated classification of cell morphology by coherence-controlled holographic microscopy 

    Štrbková, Lenka; Zicha, Daniel; Veselý, Pavel; Chmelík, Radim (SPIE, 2017-08-23)
    In the last few years, classification of cells by machine learning has become frequently used in biology. However, most of the approaches are based on morphometric (MO) features, which are not quantitative in terms of cell ...