Now showing items 58-76 of 142

  • G-Quadruplexes as Sensing Probes 

    Ruttkay-Nedecký, Branislav; Kudr, Jiří; Nejdl, Lukáš; Mašková, Darina; Kizek, René; Adam, Vojtěch (MDPI, 2013-12-01)
    Guanine-rich sequences of DNA are able to create tetrastranded structures known as G-quadruplexes; they are formed by the stacking of planar G-quartets composed of four guanines paired by Hoogsteen hydrogen bonding. ...
  • Gold Nanoparticles-Cysteine-Multiwall Carbon Nanotube Modified Electrode for Heavy Metal Ions Detection 

    Koudelková, Zuzana; Richtera, Lukáš; Švec, Pavel; Adam, Vojtěch (TANGER, 2019-02-01)
    The environmental contamination by heavy metals is one of the global problems that disturb the ecological balance. A platform for the simultaneous electrochemical detection of trace heavy metal ions has been developed based ...
  • Handheld Real-Time PCR Device 

    Ahrberg, Christian D.; Ilic, Bojan Robert; Manz, Andreas; Neužil, Pavel (Royal Society of Chemistry, 2016-01-04)
    Here we report one of the smallest real-time polymerase chain reaction (PCR) system up to date with approximate size of 100 mm × 60 mm × 33 mm. The system is an autonomous unit requiring an external 12 V power supply. Four ...
  • High strength, biodegradable and cytocompatible alpha tricalcium phosphate-iron composites for temporal reduction of bone fractures 

    Montufar Jimenez, Edgar Benjamin; Casas Luna, Mariano; Horynová, Miroslava; Tkachenko, Serhii; Fohlerová, Zdenka; Díaz de la Torre, Sebastian; Dvořák, Karel; Čelko, Ladislav; Kaiser, Jozef (Elsevier, 2018-02-09)
    In this work alpha tricalcium phosphate (a-TCP)/iron (Fe) composites were developed as a new family of biodegradable, load-bearing and cytocompatible materials. The composites with composition from pure ceramic to pure ...
  • High-throughput deposition of chemical reagents via pen-plotting technique for microfluidic paper-based analytical devices 

    Rahbar, Mohammad; Nesterenko, Pavel; Paull, Brett; Macka, Miroslav (Elsevier, 2019-01-24)
    The deposition of chemical reagent inks on paper is a crucial step in the development and fabrication of microfluidic paper-based analytical devices (mu PADs). A pen-plotting approach, delivering chemical ink deposition ...
  • hNET as a target for neuroblastoma nanomedicine 

    Charousová, Markéta; Dostálová, Simona; Haddad, Yazan Abdulmajeed Eyadh; Strmiska, Vladislav; Křížková, Soňa; Hynek, David; Milosavljević, Vedran; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    Chemotherapy often results in various side effects, which can negatively affect health. Neuroblastoma, one of the most common types of childhood cancer, is but one of the examples, where side effects of chemotherapeutic ...
  • Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma 

    Pacík, Dalibor; Plevová, Mariana; Urbanová, Lucie; Lacková, Zuzana; Strmiska, Vladislav; Nečas, Alois; Heger, Zbyněk; Adam, Vojtěch (Springer Nature, 2018-12-01)
    The hypothesis that dogs can detect malignant tumours through the identification of specific molecules is nearly 30 years old. To date, several reports have described the successful detection of distinct types of cancer. ...
  • Improved Electrochemical Detection of Zinc Ions Using Electrode Modified with Electrochemically Reduced Graphene Oxide 

    Kudr, Jiří; Richtera, Lukáš; Nejdl, Lukáš; Xhaxhiu, Kledi; Vítek, Petr; Ruttkay-Nedecký, Branislav; Hynek, David; Kopel, Pavel; Adam, Vojtěch; Kizek, René (MDPI, 2016-01-01)
    Increasing urbanization and industrialization lead to the release of metals into the biosphere, which has become a serious issue for public health. In this paper, the direct electrochemical reduction of zinc ions is studied ...
  • Improving cytocompatibility of CdTe quantum dots by Schiff-base-coordinated lanthanides surface doping 

    Buchtelová, Hana; Strmiska, Vladislav; Škubalová, Zuzana; Dostálová, Simona; Michálek, Petr; Křížková, Soňa; Hynek, David; Kalina, Lukáš; Richtera, Lukáš; Moulick, Amitava; Adam, Vojtěch; Heger, Zbyněk (BioMed Central, 2018-04-19)
    Background: Suitable fluorophores are the core of fluorescence imaging. Among the most exciting, yet controversial, labels are quantum dots (QDs) with their unique optical and chemical properties, but also considerable ...
  • In Vivo Antibacterial Study of Zinc Phosphate-based Nanoparticles 

    Kočiová, Silvia; Valečková, Vendula; Bytešníková, Zuzana; Horký, Pavel; Kopel, Pavel; Adam, Vojtěch; Šmerková, Kristýna (Tanger, 2019-02-01)
    In animal nutrition, the nanotechnology is mostly used for the preparation of nanominerals, especially trace minerals, due to their low bioavailability. These nanominerals also showed advantageous effects at lower doses ...
  • Induction of Laccase, Lignin Peroxidase and Manganese Peroxidase Activities in White-Rot Fungi Using Copper Complexes 

    Vršanská, Martina; Voběrková, Stanislava; Langer, Vratislav; Palovčíková, Dagmar; Moulick, Amitava; Adam, Vojtěch; Kopel, Pavel (MDPI, 2016-11-01)
    Ligninolytic enzymes, such as laccase, lignin peroxidase and manganese peroxidase, are biotechnologically-important enzymes. The ability of five white-rot fungal strains Daedaleopsis confragosa, Fomes fomentarius, Trametes ...
  • Influence of liposomal platinum cytostatics on cancer cells by voltammetric methods 

    Sedláčková, Eliška; Laníková, Petra; Hynek, David; Krejčová, Ludmila; Buchtelová, Hana; Richtera, Lukáš; Adam, Vojtěch (TANGER, 2018-03-31)
    Aim of this work deals with closing of cisplatin into liposomes, the study of their stability and interaction with cancer cell lines. Commercial cisplatin cytostatic was encapsulated into three types of liposomes (L8, L10 ...
  • Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer 

    Heger, Zbyněk; Gumulec, Jaromír; Ondrák, Aleš; Škoda, Jan; Zítka, Zdeněk; Cernei, Natalia Vladimirovna; Masařík, Michal; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2016-03-17)
    Herein, we present a study focused on the determination of the influence of long-distance (53 km) bicycle riding on levels of chosen biochemical urinary and serum prostate cancer (PCa) biomarkers total prostate-specific ...
  • Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure 

    Kremplová, Monika; Fialová, Dana; Nejdl, Lukáš; Hynek, David; Trnková, Libuše; Hubálek, Jaromír; Kizek, René; Adam, Vojtěch (MDPI, 2014-03-01)
    The electroactivity of purine and pyrimidine bases is the most important property of nucleic acids that is very useful for determining oligonucleotides using square wave voltammetry. This study was focused on the electrochemical ...
  • Interaction of Heavy Metal Ions with Carbon and Iron Based Particles 

    Fialová, Dana; Kremplová, Monika; Melichar, Lukáš; Kopel, Pavel; Hynek, David; Adam, Vojtěch; Kizek, René (MDPI, 2014-03-18)
    Due to the rapid development of industry and associated production of toxic waste, especially heavy metals, there is a great interest to create and upgrade new sorption materials to remove these pollutants from the ...
  • Investigating the interplay between sarcosine and Ca2+-dependent signaling in prostate cells 

    Strmiska, Vladislav; Buchtelová, Hana; Michálek, Petr; Křížková, Soňa; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2019-01-02)
    It has been shown that sarcosine supplementation stimulates proliferation and invassivenes of prostate cells. Nevertheless, the exact molecular mechanism responsible for this phenomenon is not known. In the present study ...
  • Ion exchange chromatography and mass spectrometric methods for analysis of cadmium-phytochelatin (II) complexes 

    Merlos Rodrigo, Miguel Ángel; Cernei, Natalia Vladimirovna; Komínková, Markéta; Zítka, Ondřej; Beklová, Miroslava; Zehnálek, Josef; Kizek, René; Adam, Vojtěch (MDPI, 2013-03-28)
    In this study, in vitro formed Cd-phytochelatin (PC2) complexes were characterized using ion exchange chromatography (IEC) and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. The ...
  • Ion-Exchange Based Immobilization of Chromogenic Reagents on Microfluidic Paper Analytical Devices 

    Rahbar, Mohammad; Wheeler, Aaron R.; Paull, Brett; Macka, Miroslav (American Chemical Society, 2019-07-16)
    Distance-based detection methods, as used in development of microfluidic paper analytical devices (mu PADs), rely on the dynamic formation of a colored band along the length of the paper microfluidic channels. The color ...
  • Isolation of Arginine Using Maghemite Particles 

    Cernei, Natalia Vladimirovna; Kopel, Pavel; Horký, Pavel; Zítka, Ondřej; Adam, Vojtěch (TANGER, 2019-02-01)
    In this paper, we report the optimal conditions for the isolation of amino acid arginine from different types of matrix, such as blood, plasma or tissue and their characterization using ion-exchange liquid chromatography with ...