Now showing items 71-89 of 162

  • Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma 

    Pacík, Dalibor; Plevová, Mariana; Urbanová, Lucie; Lacková, Zuzana; Strmiska, Vladislav; Nečas, Alois; Heger, Zbyněk; Adam, Vojtěch (Springer Nature, 2018-12-01)
    The hypothesis that dogs can detect malignant tumours through the identification of specific molecules is nearly 30 years old. To date, several reports have described the successful detection of distinct types of cancer. ...
  • Improved Electrochemical Detection of Zinc Ions Using Electrode Modified with Electrochemically Reduced Graphene Oxide 

    Kudr, Jiří; Richtera, Lukáš; Nejdl, Lukáš; Xhaxhiu, Kledi; Vítek, Petr; Ruttkay-Nedecký, Branislav; Hynek, David; Kopel, Pavel; Adam, Vojtěch; Kizek, René (MDPI, 2016-01-01)
    Increasing urbanization and industrialization lead to the release of metals into the biosphere, which has become a serious issue for public health. In this paper, the direct electrochemical reduction of zinc ions is studied ...
  • Improving cytocompatibility of CdTe quantum dots by Schiff-base-coordinated lanthanides surface doping 

    Buchtelová, Hana; Strmiska, Vladislav; Škubalová, Zuzana; Dostálová, Simona; Michálek, Petr; Křížková, Soňa; Hynek, David; Kalina, Lukáš; Richtera, Lukáš; Moulick, Amitava; Adam, Vojtěch; Heger, Zbyněk (BioMed Central, 2018-04-19)
    Background: Suitable fluorophores are the core of fluorescence imaging. Among the most exciting, yet controversial, labels are quantum dots (QDs) with their unique optical and chemical properties, but also considerable ...
  • In Vitro Interactions between 17 beta-Estradiol and DNA Result in Formation of the Hormone-DNA Complexes 

    Heger, Zbyněk; Guráň, Roman; Zítka, Ondřej; Beklová, Miroslava; Adam, Vojtěch; Kizek, René (MDPI, 2014-08-01)
    Beyond the role of 17 beta-estradiol (E-2) in reproduction and during the menstrual cycle, it has been shown to modulate numerous physiological processes such as cell proliferation, apoptosis, inflammation and ion transport ...
  • In Vivo Antibacterial Study of Zinc Phosphate-based Nanoparticles 

    Kočiová, Silvia; Valečková, Vendula; Bytešníková, Zuzana; Horký, Pavel; Kopel, Pavel; Adam, Vojtěch; Šmerková, Kristýna (Tanger, 2019-02-01)
    In animal nutrition, the nanotechnology is mostly used for the preparation of nanominerals, especially trace minerals, due to their low bioavailability. These nanominerals also showed advantageous effects at lower doses ...
  • Induction of Laccase, Lignin Peroxidase and Manganese Peroxidase Activities in White-Rot Fungi Using Copper Complexes 

    Vršanská, Martina; Voběrková, Stanislava; Langer, Vratislav; Palovčíková, Dagmar; Moulick, Amitava; Adam, Vojtěch; Kopel, Pavel (MDPI, 2016-11-01)
    Ligninolytic enzymes, such as laccase, lignin peroxidase and manganese peroxidase, are biotechnologically-important enzymes. The ability of five white-rot fungal strains Daedaleopsis confragosa, Fomes fomentarius, Trametes ...
  • Influence of liposomal platinum cytostatics on cancer cells by voltammetric methods 

    Sedláčková, Eliška; Laníková, Petra; Hynek, David; Krejčová, Ludmila; Buchtelová, Hana; Richtera, Lukáš; Adam, Vojtěch (TANGER, 2018-03-31)
    Aim of this work deals with closing of cisplatin into liposomes, the study of their stability and interaction with cancer cell lines. Commercial cisplatin cytostatic was encapsulated into three types of liposomes (L8, L10 ...
  • Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer 

    Heger, Zbyněk; Gumulec, Jaromír; Ondrák, Aleš; Škoda, Jan; Zítka, Zdeněk; Cernei, Natalia Vladimirovna; Masařík, Michal; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2016-03-17)
    Herein, we present a study focused on the determination of the influence of long-distance (53 km) bicycle riding on levels of chosen biochemical urinary and serum prostate cancer (PCa) biomarkers total prostate-specific ...
  • Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure 

    Kremplová, Monika; Fialová, Dana; Nejdl, Lukáš; Hynek, David; Trnková, Libuše; Hubálek, Jaromír; Kizek, René; Adam, Vojtěch (MDPI, 2014-03-01)
    The electroactivity of purine and pyrimidine bases is the most important property of nucleic acids that is very useful for determining oligonucleotides using square wave voltammetry. This study was focused on the electrochemical ...
  • Interaction of Heavy Metal Ions with Carbon and Iron Based Particles 

    Fialová, Dana; Kremplová, Monika; Melichar, Lukáš; Kopel, Pavel; Hynek, David; Adam, Vojtěch; Kizek, René (MDPI, 2014-03-18)
    Due to the rapid development of industry and associated production of toxic waste, especially heavy metals, there is a great interest to create and upgrade new sorption materials to remove these pollutants from the ...
  • Investigating the interplay between sarcosine and Ca2+-dependent signaling in prostate cells 

    Strmiska, Vladislav; Buchtelová, Hana; Michálek, Petr; Křížková, Soňa; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2019-01-02)
    It has been shown that sarcosine supplementation stimulates proliferation and invassivenes of prostate cells. Nevertheless, the exact molecular mechanism responsible for this phenomenon is not known. In the present study ...
  • Ion exchange chromatography and mass spectrometric methods for analysis of cadmium-phytochelatin (II) complexes 

    Merlos Rodrigo, Miguel Ángel; Cernei, Natalia Vladimirovna; Komínková, Markéta; Zítka, Ondřej; Beklová, Miroslava; Zehnálek, Josef; Kizek, René; Adam, Vojtěch (MDPI, 2013-03-28)
    In this study, in vitro formed Cd-phytochelatin (PC2) complexes were characterized using ion exchange chromatography (IEC) and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. The ...
  • Ion-Exchange Based Immobilization of Chromogenic Reagents on Microfluidic Paper Analytical Devices 

    Rahbar, Mohammad; Wheeler, Aaron R.; Paull, Brett; Macka, Miroslav (American Chemical Society, 2019-07-16)
    Distance-based detection methods, as used in development of microfluidic paper analytical devices (mu PADs), rely on the dynamic formation of a colored band along the length of the paper microfluidic channels. The color ...
  • Isolation of Arginine Using Maghemite Particles 

    Cernei, Natalia Vladimirovna; Kopel, Pavel; Horký, Pavel; Zítka, Ondřej; Adam, Vojtěch (TANGER, 2019-02-01)
    In this paper, we report the optimal conditions for the isolation of amino acid arginine from different types of matrix, such as blood, plasma or tissue and their characterization using ion-exchange liquid chromatography with ...
  • The Isolation of DNA by Polycharged Magnetic Particles: An Analysis of the Interaction by Zeta Potential and Particle Size 

    Haddad, Yazan Abdulmajeed Eyadh; Xhaxhiu, Kledi; Kopel, Pavel; Hynek, David; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2016-04-20)
    Magnetic isolation of biological targets is in major demand in the biotechnology industry today. This study considers the interaction of four surface-modified magnetic micro- and nanoparticles with selected DNA fragments. ...
  • Isolation of histamine using -Fe2O3 nanoparticles 

    Gagić, Milica; Kopel, Pavel; Milosavljević, Vedran; Cernei, Natalia Vladimirovna; Zítka, Ondřej; Švec, Pavel; Jamroz, Ewelina; Adam, Vojtěch (Mendel University in Brno, 2019-01-02)
    Histamine, biologically active amine, is normally present in the body and it is involved in a local regulation of physiological processes. It occurs in food as a product of microbial decarboxylation of the amino acid ...
  • Jacks of metal/metalloid chelation trade in plants - an overview 

    Anjum, Naser A.; Hasanuzzaman, Mirza; Hossain, Mohammad Anwar; Thangavel, Palaniswamy; Roychoudhury, Aryadeep; Sarvajeet, Singh Gill; Merlos Rodrigo, Miguel Ángel; Adam, Vojtěch; Fujita, Masayuki; Kizek, René; Da Costa Duarte, Armando; Pereira, Eduarda; Ahmad, Iqbal (Frontiers, 2015-04-02)
    Varied environmental compartments including soil sarebeingcontaminatedbyamyriadtoxicmetal(loid)s(hereaftertermedas metal/s )mainlythroughanthropogenicactivities.Thesemetalsmaycontaminatefoodchainandbringirreparableconseq ...
  • LA-ICP-MS as a sensitive method for detection of nanoparticle-antibody conjugates in immunochemistry analysis 

    Vlčnovská, Marcela; Tvrdoňová, Michaela; Štossová, Aneta; Polanská, Hana; Vaculovičová, Markéta; Vaculovič, Tomáš; Masařík, Michal (Mendel University in Brno, 2019-12-31)
    Laser ablation followed by inductively coupled plasma mass spectrometry is an analytical method suitable for low concentration measurement of elements in a sample. This can be used not only for detection of elemental ...
  • Lead Ions Encapsulated in Liposomes and Their Effect on Staphylococcus aureus 

    Kenšová, Renáta; Blažková, Iva; Konečná, Marie; Kopel, Pavel; chudobova, Dagmar; Zítka, Ondřej; Vaculovičová, Markéta; Hynek, David; Adam, Vojtěch; Beklová, Miroslava; Kizek, René (MDPI, 2013-12-01)
    The aim of the study was the preparation of a liposome complex with encapsulated lead ions, which were electrochemically detected. In particular, experiments were focused on the potential of using an electrochemical method ...