Now showing items 81-100 of 142

  • Magnetic Molecularly Imprinted Polymers Used for Staphylococcus Aureus Isolation and Detection 

    Zelníčková, Jaroslava; Hutařová, Jitka; Vaculovičová, Markéta (TANGER, 2019-02-01)
    A sensitive detection of microorganisms plays an important role in prevention and identification of infectious and deadly diseases. However, conventional methods of bacterial detection are time-consuming, laborious ...
  • Magnetic nanoparticles: From Design and Synthesis to Real World Applications 

    Kudr, Jiří; Haddad, Yazan Abdulmajeed Eyadh; Richtera, Lukáš; Heger, Zbyněk; Černák, Mirko; Adam, Vojtěch; Zítka, Ondřej (MDPI, 2017-09-01)
    The increasing number of scientific publications focusing on magnetic materials indicates growing interest in the broader scientific community. Substantial progress was made in the synthesis of magnetic materials of desired ...
  • MALDI MSI of MeLiM melanoma: Searching for differences in protein profiles 

    Guráň, Roman; Pompeiano Vaníčková, Lucie; Horák, Vratislav; Křížková, Soňa; Michálek, Petr; Heger, Zbyněk; Zítka, Ondřej; Adam, Vojtěch (PLOS, 2017-12-08)
    Background Treatment of advanced cutaneous melanoma remains challenging, and new data on melanoma biology are required. The most widely accepted criteria for the prognostic evaluation of melanoma are histopathological and ...
  • MALDI-TOF MSI method for determining spatial distribution of infection markers in pulmonary tissues of pigs 

    Do, Tomáš; Jarošová, Rea; Ilieva, Lada; Guráň, Roman; Ondráčková, Petra; Faldyna, Martin; Sládek, Zbyšek; Zítka, Ondřej (Mendel University in Brno, 2019-01-02)
    In recent years the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry imaging (MALDI-TOF MSI) is used for molecular mapping of diverse biomarkers such as proteins or peptides in animal/plant ...
  • Mathematical evaluation of the amino acid and polyphenol content and antioxidant activities of fruits from different apricot cultivars 

    Sochor, Jiří; Škutková, Helena; Babula, Petr; Zítka, Ondřej; Cernei, Natalia Vladimirovna; Rop, Otakar; Krška, Boris; Adam, Vojtěch; Provazník, Ivo; Kizek, René (MDPI, 2011-09-01)
    Functional foods are of interest because of their significant effects on human health, which can be connected with the presence of some biologically important compounds. In this study, we carried out complex analysis of ...
  • Metallothionein – Immunohistochemical Cancer Biomarker: A Meta-Analysis 

    Gumulec, Jaromír; Raudenská, Martina; Adam, Vojtěch; Kizek, René; Masařík, Michal (PLOS, 2014-01-08)
    Metallothionein (MT) has been extensively investigated as a molecular marker of various types of cancer. In spite of the fact that numerous reviews have been published in this field, no meta-analytical approach has been ...
  • Microwave-assisted synthesis of goethite nanoparticles used for removal of Cr(VI) from aqueous solution 

    Nguyen, Dính Vinh; Kynický, Jindřich; Ambrožová, Pavlína; Adam, Vojtěch (MDPI, 2017-07-01)
    The microwave-assisted synthesis of goethite nanoparticles has been studied. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential ...
  • Modern Micro and Nanoparticle-Based Imaging Techniques 

    Vaculovičová, Markéta; Pekárková, Jana; Drbohlavová, Jana; Kopel, Pavel; Babula, Petr; Hynek, David; Adam, Vojtěch; Eckschlager, Tomáš; Hubálek, Jaromír; Stiborová, Marie; Kaiser, Jozef; Kizek, René (MDPI, 2012-11-02)
    The requirements for early diagnostics as well as effective treatment of insidious diseases such as cancer constantly increase the pressure on development of efficient and reliable methods for targeted drug/gene delivery ...
  • Modification of electrothermal atomic absorption spectrometry for determination of arsenic in high salinity samples 

    Smolíková, Vendula; Pelcová, Pavlína; Hedbávný, Josef; Zlámalová, Lucie; Ridošková, Andrea (Mendel University in Brno, 2019-01-02)
    The electrothermal atomic absorption spectrometry (ET-AAS) method was optimized for determination of the arsenic content in high salinity samples. The combination of palladium (1 g/l) modifier, graphite furnace temperature ...
  • Molecular imprinting technology for targeted analysis of proteins 

    Hutařová, Jitka; Vaněčková, Tereza; Vaculovičová, Markéta; Adam, Vojtěch (Mendel University in Brno, 2017-12-31)
    Molecular imprinting has appeared to be an effective technique for creating of selective recognition sites in synthetic polymers. This procedure comprises polymerization of monomer in a presence of target molecules (template). ...
  • Nanoliter-sized overheated reactor 

    Neužil, Pavel; Sun, Wanxin; Karásek, Tomáš; Manz, Andreas (AIP Publishing, 2015-01-16)
    We report on a microfluidic system formed by 200 nl water droplets, encapsulated by a 600 nl mineral oil placed on a hydrophobically coated glass microscope cover slip. The micromachined heater underneath the glass was ...
  • Nanoparticles Based on Essential Metals and Their Phytotoxicity 

    Kryštofová, Olga; Nejdl, Lukáš; Adam, Vojtěch (Springer Nature, 2017-04-26)
    Nanomaterials in agriculture are becoming popular due to the impressive advantages of these particles. However, their bioavailability and toxicity are key features for their massive employment. Herein, we comprehensively ...
  • Nanoparticles Suitable for BCAA Isolation Can Serve for Use in Magnetic Lipoplex-Based Delivery System for L, I, V, or R-rich Antimicrobial Peptides 

    Veselý, Radek; Jelínková, Pavlína; Hegerová, Dagmar; Cernei, Natalia Vladimirovna; Kopel, Pavel; Moulick, Amitava; Richtera, Lukáš; Heger, Zbyněk; Adam, Vojtěch; Zítka, Ondřej (MDPI, 2016-04-01)
    This paper investigates the synthesis of paramagnetic nanoparticles, which are able to bind branched chain amino acids (BCAAs)—leucine, valine, and isoleucine and, thus, serve as a tool for their isolation. Further, by ...
  • Nanostructured Polypyrrole-Based Ammonia and Volatile Organic Compound Sensors 

    Šetka, Milena; Drbohlavová, Jana; Hubálek, Jaromír (MDPI, 2017-03-10)
    The aim of this review is to summarize the recent progress in the fabrication of efcient nanostructured polymer-based sensors with special focus on polypyrrole. The correlation between physico-chemical parameters, mainly ...
  • A New Method for 2D Materials Properties Modulation by Controlled Induced Mechanical Strain 

    Gablech, Imrich; Pekárek, Jan; Klempa, Jaroslav; Vyroubal, Petr; Svatoš, Vojtěch; Neužil, Pavel (MDPI, 2018-12-07)
    This paper proposes a new method for characterization of 2D materials under the precisely specified conditions. It is achieved by integration of a 2D material as a field effect transistors structures with a piezoelectric ...
  • A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Kudr, Jiří; Gumulec, Jaromír; Blažková, Iva; Zítka, Ondřej; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch; Kizek, René (MDPI, 2013-11-01)
    Doxorubicin is a commonly used antineoplastic agent in the treatment of many types of cancer. Little is known about the interactions of doxorubicin with cardiac biomolecules. Serious cardiotoxicity including dilated ...
  • Novel Vancomycin-Peptide Conjugate as Potent Antibacterial Agent against Vancomycin-Resistant Staphylococcus aureus 

    Jelínková, Pavlína; Šplíchal, Zbyněk; Jimenez Jimenez, Ana Maria; Haddad, Yazan Abdulmajeed Eyadh; Mazumdar, Aninda; Sur, Vishma Pratap; Milosavljević, Vedran; Kopel, Pavel; Buchtelová, Hana; Guráň, Roman; Zítka, Ondřej; Richtera, Lukáš; Hegerová, Dagmar; Heger, Zbyněk; Moulick, Amitava; Adam, Vojtěch (Dove Press, 2018-11-01)
    Background: Increase in vancomycin (Van)-resistant bacterial strains including vancomycin-resistant Staphylococcus aureus (VRSA) and lack of new effective antibiotics have become a formidable health problem. Materials and ...
  • On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro 

    Jang, Mi; Neužil, Pavel; Volk, Thomas; Manz, Andreas; Kleber, Astrid (AIP Publishing, 2015-06-23)
    The in vitro study of liver functions and liver cell specific responses to external stimuli deals with the problem to preserve the in vivo functions of primary hepatocytes. In this study, we used the biochip OrganoPlateTM ...
  • Optimalization of DNA isolation process in freshwater microalgae using homogenizer 

    Bačová, Romana; Koláčková, Martina; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    Last decades microalgae are gaining much interest due to high-valued biomolecules content. Increasing number of genetic studies and modifications require quality input material and short time analysis at the same time. ...
  • Oxidative Stress Resistance in Metastatic Prostate Cancer: Renewal by Self-Eating 

    Balvan, Jan; Gumulec, Jaromír; Raudenská, Martina; Křížová, Aneta; Štěpka, Petr; Babula, Petr; Kizek, René; Adam, Vojtěch; Masařík, Michal (PLOS, 2015-12-15)
    Resistant cancer phenotype is a key obstacle in the successful therapy of prostate cancer. The primary aim of our study was to explore resistance mechanisms in the advanced type of prostate cancer cells (PC-3) and to clarify ...