Now showing items 102-121 of 159

  • Nanocomposite furcellaran films - The influence of nanofillers on functional properties of furcellaran films and effect on linseed oil preservation 

    Jamroz, Ewelina; Kopel, Pavel; Tkaczewska, Joanna; Dordevič, Dani; Jančíková, Simona; Kulawik, Piotr; Milosavljević, Vedran; Doleželíková, Kristýna; Šmerková, Kristýna; Švec, Pavel; Adam, Vojtěch (MDPI, 2019-12-09)
    Nanocomposite films that were based on furcellaran (FUR) and nanofillers (carbon quantum dots (CQDs), maghemite nanoparticles (MAN), and graphene oxide (GO)) were obtained by the casting method. The microstructure, as well ...
  • Nanoliter-sized overheated reactor 

    Neužil, Pavel; Sun, Wanxin; Karásek, Tomáš; Manz, Andreas (AIP Publishing, 2015-01-16)
    We report on a microfluidic system formed by 200 nl water droplets, encapsulated by a 600 nl mineral oil placed on a hydrophobically coated glass microscope cover slip. The micromachined heater underneath the glass was ...
  • Nanoparticles Based on Essential Metals and Their Phytotoxicity 

    Kryštofová, Olga; Nejdl, Lukáš; Adam, Vojtěch (Springer Nature, 2017-04-26)
    Nanomaterials in agriculture are becoming popular due to the impressive advantages of these particles. However, their bioavailability and toxicity are key features for their massive employment. Herein, we comprehensively ...
  • Nanoparticles Suitable for BCAA Isolation Can Serve for Use in Magnetic Lipoplex-Based Delivery System for L, I, V, or R-rich Antimicrobial Peptides 

    Veselý, Radek; Jelínková, Pavlína; Hegerová, Dagmar; Cernei, Natalia Vladimirovna; Kopel, Pavel; Moulick, Amitava; Richtera, Lukáš; Heger, Zbyněk; Adam, Vojtěch; Zítka, Ondřej (MDPI, 2016-04-01)
    This paper investigates the synthesis of paramagnetic nanoparticles, which are able to bind branched chain amino acids (BCAAs)—leucine, valine, and isoleucine and, thus, serve as a tool for their isolation. Further, by ...
  • Nanostructured Polypyrrole-Based Ammonia and Volatile Organic Compound Sensors 

    Šetka, Milena; Drbohlavová, Jana; Hubálek, Jaromír (MDPI, 2017-03-10)
    The aim of this review is to summarize the recent progress in the fabrication of efcient nanostructured polymer-based sensors with special focus on polypyrrole. The correlation between physico-chemical parameters, mainly ...
  • A New Method for 2D Materials Properties Modulation by Controlled Induced Mechanical Strain 

    Gablech, Imrich; Pekárek, Jan; Klempa, Jaroslav; Vyroubal, Petr; Svatoš, Vojtěch; Neužil, Pavel (MDPI, 2018-12-07)
    This paper proposes a new method for characterization of 2D materials under the precisely specified conditions. It is achieved by integration of a 2D material as a field effect transistors structures with a piezoelectric ...
  • A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Kudr, Jiří; Gumulec, Jaromír; Blažková, Iva; Zítka, Ondřej; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch; Kizek, René (MDPI, 2013-11-01)
    Doxorubicin is a commonly used antineoplastic agent in the treatment of many types of cancer. Little is known about the interactions of doxorubicin with cardiac biomolecules. Serious cardiotoxicity including dilated ...
  • Novel Ruthenium coordinate compound combined with Schiff base and benzimidazole as a potent antibacterial agent against VRSA and MRSA 

    Sur, Vishma Pratap; Mazumdar, Aninda; Kopel, Pavel; Moulick, Amitava (Mendel University in Brno, 2019-12-31)
    The rise of antibiotic-resistant strains is an important public health problem and thus the development of an alternative to antibiotics is imminent. The Ruthenium–Schiff base with benzimidazole (RU–S2), a co-ordinate ...
  • Novel Vancomycin-Peptide Conjugate as Potent Antibacterial Agent against Vancomycin-Resistant Staphylococcus aureus 

    Jelínková, Pavlína; Šplíchal, Zbyněk; Jimenez Jimenez, Ana Maria; Haddad, Yazan Abdulmajeed Eyadh; Mazumdar, Aninda; Sur, Vishma Pratap; Milosavljević, Vedran; Kopel, Pavel; Buchtelová, Hana; Guráň, Roman; Zítka, Ondřej; Richtera, Lukáš; Hegerová, Dagmar; Heger, Zbyněk; Moulick, Amitava; Adam, Vojtěch (Dove Press, 2018-11-01)
    Background: Increase in vancomycin (Van)-resistant bacterial strains including vancomycin-resistant Staphylococcus aureus (VRSA) and lack of new effective antibiotics have become a formidable health problem. Materials and ...
  • On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro 

    Jang, Mi; Neužil, Pavel; Volk, Thomas; Manz, Andreas; Kleber, Astrid (AIP Publishing, 2015-06-23)
    The in vitro study of liver functions and liver cell specific responses to external stimuli deals with the problem to preserve the in vivo functions of primary hepatocytes. In this study, we used the biochip OrganoPlateTM ...
  • Optimalization of DNA isolation process in freshwater microalgae using homogenizer 

    Bačová, Romana; Koláčková, Martina; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    Last decades microalgae are gaining much interest due to high-valued biomolecules content. Increasing number of genetic studies and modifications require quality input material and short time analysis at the same time. ...
  • Oxidative Stress Resistance in Metastatic Prostate Cancer: Renewal by Self-Eating 

    Balvan, Jan; Gumulec, Jaromír; Raudenská, Martina; Křížová, Aneta; Štěpka, Petr; Babula, Petr; Kizek, René; Adam, Vojtěch; Masařík, Michal (PLOS, 2015-12-15)
    Resistant cancer phenotype is a key obstacle in the successful therapy of prostate cancer. The primary aim of our study was to explore resistance mechanisms in the advanced type of prostate cancer cells (PC-3) and to clarify ...
  • Papillomavirus infection of roe deer in the Czech Republic and fibropapilloma-associated levels of metallothionein, zinc, and oxidative stress 

    Král, Jiří; Banďouchová, Hana; Brichta, Jiří; Kovacova, Veronika; Ondráček, Karel; Osičková, Jitka; Hrubá, Hana; Hutařová, Zdeňka; Komínková, Markéta; Cernei, Natalia Vladimirovna; Konečná, Marie; Tmejová, Kateřina; Zítka, Ondřej; Adam, Vojtěch; Kízek, René; Skoric, Misa; Tremlová, Bohuslava; Treml, František; Pikula, Jiří (University of Veterinary and Pharmaceutical Sciences, 2015-06-01)
    The present study aimed at the aetiological diagnosis of skin tumours of roe deer (Capreolus capreolus) in the Czech Republic. A total of 33 roe deer specimens showing skin masses were sampled for histopathology, virus ...
  • Paramagnetic Nanoparticles as a Platform for FRET-Based Sarcosine Picomolar Detection 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Křížková, Soňa; Masařík, Michal; Kopel, Pavel; Hodek, Petr; Zítka, Ondřej; Adam, Vojtěch; Kizek, René (Nature Publishing Group, 2015-03-09)
    Herein, we describe an ultrasensitive specific biosensing system for detection of sarcosine as a potential biomarker of prostate carcinoma based on Forster resonance energy transfer (FRET). The FRET biosensor employs ...
  • Perspective of Use of Antiviral Peptides against Influenza Virus 

    Skaličková, Sylvie; Heger, Zbyněk; Krejčová, Ludmila; Pekařík, Vladimír; Bastl, Karel; Janda, Jozef; Kostolanský, František; Vařečková, Eva; Zítka, Ondřej; Adam, Vojtěch; Kizek, René (MDPI, 2015-10-01)
    The threat of a worldwide influenza pandemic has greatly increased over the past decade with the emergence of highly virulent avian influenza strains. The increased frequency of drug-resistant influenza strains against ...
  • Phenolic profile of edible honeysuckle berries (Genus Lonicera) and their biological effect 

    Juříková, Tunde; Rop, Otakar; Mlček, Jiří; Sochor, Jiří; Balla, Štefan; Szekeres, Ladislav; Hegedusová, A.; Hubálek, Jaromír; Adam, Vojtěch; Kizek, René (MDPI, 2012-01-01)
    The current status of research on polyphenolic compounds in the berries of edible honeysuckle and their biological effects, including recommended utilization, are reviewed. The major classes of phenolic compounds in the ...
  • Platinum nanoparticles induce damage to DNA and inhibit DNA replication 

    Nejdl, Lukáš; Kudr, Jiří; Moulick, Amitava; Hegerová, Dagmar; Ruttkay-Nedecký, Branislav; Gumulec, Jaromír; Číhalová, Kristýna; Šmerková, Kristýna; Dostálová, Simona; Křížková, Soňa; Novotná, Marie; Kopel, Pavel; Adam, Vojtěch (PLOS, 2017-07-12)
    Sparsely tested group of platinum nanoparticles (PtNPs) may have a comparable effect as complex platinum compounds. The aim of this study was to observe the effect of PtNPs in in vitro amplification of DNA fragment of phage ...
  • Preparation and Characterisation of Highly Stable Iron Oxide Nanoparticles for Magnetic Resonance Imaging 

    Kovář, David; Hubálek, Jaromír; Fohlerová, Zdenka; Malá, Aneta; Kalina, Michal; Jiřík, Radovan; Hlaváček, Antonín; Slabý, Ondřej; Skládal, Petr; Farka, Zdeněk; Mlčochová, Jitka; Starčuk jr., Zenon (Hindawi Publishing Corporation, 2017-02-23)
    Magnetic nanoparticles produced using aqueous coprecipitation usually exhibit wide particle size distribution. Synthesis of small and uniform magnetic nanoparticles has been the subject of extensive research over recent ...
  • Preparation and Optimisation of Cross-Linked Enzyme Aggregates Using Native Isolate White Rot Fungi Trametes versicolor and Fomes fomentarius for the Decolourisation of Synthetic Dyes 

    Vršanská, Martina; Voběrková, Stanislava; Jimenez Jimenez, Ana Maria; Strmiska, Vladislav; Adam, Vojtěch (MDPI, 2018-01-01)
    The key to obtaining an optimum performance of an enzyme is often a question of devising a suitable enzyme and optimisation of conditions for its immobilization. In this study, laccases from the native isolates of white ...
  • Preparation of cryosections from frozen porcine pulmonary tissue for MALDI mass spectrometry imaging 

    Jarošová, Rea; Smolíková, Vendula; Dvořák, Marek; Guráň, Roman; Do, Tomáš; Ondráčková, Petra; Zítka, Ondřej; Sládek, Zbyšek (Mendel University in Brno, 2019-01-02)
    In last decades, a matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) was used for mapping the spatial distribution of different molecules, mainly peptides, proteins, lipids and metabolites, ...