Now showing items 21-40 of 299

  • How Do Grass Species, Season and Ensiling Influence Mycotoxin Content in Forage? 

    Skládanka, Jiří; Adam, Vojtěch; Doležal, Petr; Nedělník, Jan; Kizek, René; Lindušková, Hana; Mejía, Jhonny Edison Alba; Nawrath, adam (MDPI, 2013-11-01)
    Mycotoxins are secondary metabolites produced by fungal species that have harmful effects on mammals. The aim of this study was to assess the content of mycotoxins in fresh-cut material of selected forage grass species ...
  • A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Kudr, Jiří; Gumulec, Jaromír; Blažková, Iva; Zítka, Ondřej; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch; Kizek, René (MDPI, 2013-11-01)
    Doxorubicin is a commonly used antineoplastic agent in the treatment of many types of cancer. Little is known about the interactions of doxorubicin with cardiac biomolecules. Serious cardiotoxicity including dilated ...
  • Lead Ions Encapsulated in Liposomes and Their Effect on Staphylococcus aureus 

    Kenšová, Renáta; Blažková, Iva; Konečná, Marie; Kopel, Pavel; chudobova, Dagmar; Zítka, Ondřej; Vaculovičová, Markéta; Hynek, David; Adam, Vojtěch; Beklová, Miroslava; Kizek, René (MDPI, 2013-12-01)
    The aim of the study was the preparation of a liposome complex with encapsulated lead ions, which were electrochemically detected. In particular, experiments were focused on the potential of using an electrochemical method ...
  • Water-dispersible TiO2 nanoparticles via a biphasic solvothermal reaction method 

    Mohan, Rajneesh; Drbohlavová, Jana; Hubálek, Jaromír (Springer, 2013-12-01)
    Syntéza ve vodě rozpustných nanočástic z oxidu titaničitého byla dosažena solvotermální dvoufázovou metodou v autoklávu. Byl studován vliv teploty a doby přípravy a dále modifikačních ligandů na stabilitu nanočástic.
  • G-Quadruplexes as Sensing Probes 

    Ruttkay-Nedecký, Branislav; Kudr, Jiří; Nejdl, Lukáš; Mašková, Darina; Kizek, René; Adam, Vojtěch (MDPI, 2013-12-01)
    Guanine-rich sequences of DNA are able to create tetrastranded structures known as G-quadruplexes; they are formed by the stacking of planar G-quartets composed of four guanines paired by Hoogsteen hydrogen bonding. ...
  • Beads-Based Electrochemical Assay for the Detection of Influenza Hemagglutinin Labeled with CdTe Quantum Dots 

    Krejčová, Ludmila; Nejdl, Lukáš; Hynek, David; Křížková, Soňa; Kopel, Pavel; Adam, Vojtěch; Kizek, René (MDPI, 2013-12-13)
    In this study we describe a beads-based assay for rapid, sensitive and specific isolation and detection of influenza vaccine hemagglutinin (HA). Amplification of the hemagglutinin signal resulted from binding of an ...
  • Metallothionein – Immunohistochemical Cancer Biomarker: A Meta-Analysis 

    Gumulec, Jaromír; Raudenská, Martina; Adam, Vojtěch; Kizek, René; Masařík, Michal (PLOS, 2014-01-08)
    Metallothionein (MT) has been extensively investigated as a molecular marker of various types of cancer. In spite of the fact that numerous reviews have been published in this field, no meta-analytical approach has been ...
  • Flow Injection Analysis with Electrochemical Detection for Rapid Identification of Platinum-Based Cytostatics and Platinum Chlorides in Water 

    Komínková, Markéta; Heger, Zbyněk; Zítka, Ondřej; Kynický, Jindřich; Pohanka, Miroslav; Beklová, Miroslava; Adam, Vojtěch; Kizek, René (MDPI, 2014-02-04)
    Platinum-based cytostatics, such as cisplatin, carboplatin or oxaliplatin are widely used agents in the treatment of various types of tumors. Large amounts of these drugs are excreted through the urine of patients into ...
  • Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure 

    Kremplová, Monika; Fialová, Dana; Nejdl, Lukáš; Hynek, David; Trnková, Libuše; Hubálek, Jaromír; Kizek, René; Adam, Vojtěch (MDPI, 2014-03-01)
    The electroactivity of purine and pyrimidine bases is the most important property of nucleic acids that is very useful for determining oligonucleotides using square wave voltammetry. This study was focused on the electrochemical ...
  • Interaction of Heavy Metal Ions with Carbon and Iron Based Particles 

    Fialová, Dana; Kremplová, Monika; Melichar, Lukáš; Kopel, Pavel; Hynek, David; Adam, Vojtěch; Kizek, René (MDPI, 2014-03-18)
    Due to the rapid development of industry and associated production of toxic waste, especially heavy metals, there is a great interest to create and upgrade new sorption materials to remove these pollutants from the ...
  • From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC) 

    Neužil, Pavel (Royal Society of Chemistry, 2014-03-25)
    We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current ...
  • Trithiocyanurate Complexes of Iron, Manganese and Nickel and Their Anticholinesterase Activity 

    Kopel, Pavel; Doležal, Karel; Langer, Vratislav; Jun, Daniel; Adam, Vojtěch; Kuča, Kamil; Kizek, René (MDPI, 2014-04-08)
    The complexes of Fe(II), Mn(II) and Ni(II) with a combination of a Schiff base, nitrogen-donor ligand or macrocyclic ligand and trithiocyanuric acid (ttcH3) were prepared and characterized by elemental analysis and ...
  • Serum and Tissue Zinc in Epithelial Malignancies: A Meta-Analysis 

    Gumulec, Jaromír; Masařík, Michal; Adam, Vojtěch; Eckschlager, Tomáš; Provazník, Ivo; Kizek, René (PLOS, 2014-06-19)
    Background and Objectives: Current studies give us inconsistent results regarding the association of neoplasms and zinc(II) serum and tissues concentrations. The results of to-date studies using meta-analysis are summarized ...
  • HIV Biosensors – The Potential of the Electrochemical Way 

    Merlos Rodrigo, Miguel Ángel; Heger, Zbyněk; Cernei, Natalia Vladimirovna; Jimenez Jimenez, Ana Maria; Zítka, Ondřej; Adam, Vojtěch; Kizek, René (ESG, 2014-07-01)
    Because of high costs and time consuming common HIV tests, new ways in diagnosis, offering rapid, cheap, and accuracy possibility are looking for. One of the most promising fields is electrochemistry, providing very good ...
  • Electrochemical Sensors and Biosensors for Influenza Detection – Literature Survey 2012-2013 

    Krejčová, Ludmila; Hynek, David; Michálek, Petr; Milosavljević, Vedran; Kopel, Pavel; Zítka, Ondřej; Novotná, Marie; Kynický, Jindřich; Adam, Vojtěch; Hubálek, Jaromír; Kizek, René (ESG, 2014-07-01)
    This review summarized published information in the area of electrochemical detection of influenza virus in 2012 – 2013. The attention was mainly paid to summarize the news in the field of sensors and biosensors for influenza ...
  • In Vitro Interactions between 17 beta-Estradiol and DNA Result in Formation of the Hormone-DNA Complexes 

    Heger, Zbyněk; Guráň, Roman; Zítka, Ondřej; Beklová, Miroslava; Adam, Vojtěch; Kizek, René (MDPI, 2014-08-01)
    Beyond the role of 17 beta-estradiol (E-2) in reproduction and during the menstrual cycle, it has been shown to modulate numerous physiological processes such as cell proliferation, apoptosis, inflammation and ion transport ...
  • Algal Biomass Analysis by Laser-Based Analytical Techniques - A Review 

    Pořízka, Pavel; Prochazková, Petra; Prochazka, David; Sládková, Lucia; Novotný, Jan; Petrilak, Michal; Brada, Michal; Samek, Ota; Pilát, Zdeněk; Zemánek, Pavel; Adam, Vojtěch; Kizek, René; Novotný, Karel; Kaiser, Jozef (MDPI, 2014-09-23)
    Algal biomass that is represented mainly by commercially grown algal strains has recently found many potential applications in various fields of interest. Its utilization has been found advantageous in the fields of ...
  • Modulation of Induced Cytotoxicity of Doxorubicin by Using Apoferritin and Liposomal Cages 

    Gumulec, Jaromír; Fojtů, Michaela; Raudenská, Martina; Sztalmachová, Markéta; Skotáková, Anna; Vlachová, Jana; Skaličková, Sylvie; Nejdl, Lukáš; Kopel, Pavel; Knopfová, Lucia; Adam, Vojtěch; Kizek, René; Stiborová, Marie; Babula, Petr; Masařík, Michal (MDPI, 2014-12-01)
    Doxorubicin is an effective chemotherapeutic drug, however, its toxicity is a significant limitation in therapy. Encapsulation of doxorubicin inside liposomes or ferritin cages decreases cardiotoxicity while maintaining ...
  • Fast response hydrogen microsensor based on semiconductor niobium-oxide nanostructures via smart anodizing of Al/Nb metal layers 

    Vazquez, Rosa Maria; Mozalev, Alexander; Llobet, Eduard (Elsevier, 2014-12-31)
    Nanostructured niobium oxide semiconductor is gaining increasing attention as electro-optic and gas sensing material. However, the preparation of stable niobium oxide nanofilm with reproducible morphology and behaviour ...
  • Simultaneous Automatic Electrochemical Detection of Zinc, Cadmium, Copper and Lead Ions in Environmental Samples Using a Thin-Film Mercury Electrode and an Artificial Neural Network 

    Kudr, Jiří; Nguyen, Hoai Viet; Gumulec, Jaromír; Nejdl, Lukáš; Blažková, Iva; Ruttkay-Nedecký, Branislav; Hynek, David; Kynický, Jindřich; Adam, Vojtěch; Kizek, René (MDPI, 2015-01-01)
    In this study a device for automatic electrochemical analysis was designed. A three electrodes detection system was attached to a positioning device, which enabled us to move the electrode system from one well to another ...