Browsing Experimentální biofotonika by Subject "small molecule drug"

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  • Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds 

    Palušová, Veronika; Renzová, Tereza; Verlande, Amandine; Vaclová, Tereza; Medková, Michaela; Cetlová, Linda; Sedláčková, Miroslava; Hříbková, Hana; Slaninová, Iva; Krutá, Miriama; Rotrekl, Vladimír; Uhlířová, Hana; Křížová, Aneta; Chmelík, Radim; Veselý, Pavel; Krafčíková, Michaela; Trantírek, Lukáš; Schink, Kay Oliver; Uldrijan, Stjepan (MDPI, 2020-06-01)
    BRAF inhibitors can delay the progression of metastatic melanoma, but resistance usually emerges, leading to relapse. Drugs simultaneously targeting two or more pathways essential for cancer growth could slow or prevent ...