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  • Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds 

    Palušová, Veronika; Renzová, Tereza; Verlande, Amandine; Vaclová, Tereza; Medková, Michaela; Cetlová, Linda; Sedláčková, Miroslava; Hříbková, Hana; Slaninová, Iva; Krutá, Miriama; Rotrekl, Vladimír; Uhlířová, Hana; Křížová, Aneta; Chmelík, Radim; Veselý, Pavel; Krafčíková, Michaela; Trantírek, Lukáš; Schink, Kay Oliver; Uldrijan, Stjepan (MDPI, 2020-06-01)
    BRAF inhibitors can delay the progression of metastatic melanoma, but resistance usually emerges, leading to relapse. Drugs simultaneously targeting two or more pathways essential for cancer growth could slow or prevent ...
  • Neurovascular Network Explorer 2.0: A Database of 2-Photon Single Vessel Diameter Measurements from Mouse SI Cortexin Response To Optogenetic Stimulation 

    Uhlířová, Hana; Peifang, Tiam; Kilic, Kivilcim; Thunemann, Martin; Sridhar, Vishnu B.; Bartsch, Hauke; Dale, Anders M.; Devor, Anna; Saisan, Payam A. (Frontiers, 2017-02-01)
    Here, we present a novel database containing 2-photon data from our recently published experimental study (Uhlirova et al., 2016a) and a second generation of our GUI-based software engine that we call NNE 2.0. The data, ...