Recent Submissions

  • Translational Studies on the Potential of a VEGF Nanoparticle-Loaded Hyaluronic Acid Hydrogel 

    O’Dwyer, Joanne; Murphy, Robert; González-Vázquez, Arlyng; Kovářová, Lenka; Pravda, Martin; Velebný, Vladimír; Heise, Andreas; Duffy, Garry P.; Cryan, Sally Ann (MDPI, 2021-05-22)
    Heart failure has a five-year mortality rate approaching 50%. Inducing angiogenesis following a myocardial infarction is hypothesized to reduce cardiomyocyte death and tissue damage, thereby preventing heart failure. Herein, ...
  • Conductive Polymer PEDOT:PSS-Based Platform for Embryonic Stem-Cell Differentiation 

    Šafaříková, Eva; Ehlich, Jiří; Stříteský, Stanislav; Vala, Martin; Weiter, Martin; Pacherník, Jiří; Kubala, Lukáš; Víteček, Jan (MDPI, 2022-01-20)
    Organic semiconductors are constantly gaining interest in regenerative medicine. Their tunable physico-chemical properties, including electrical conductivity, are very promising for the control of stem-cell differentiation. ...
  • Effect of alkali salts on the hydration process of belite clinker 

    Iliushchenko, Valeriia; Kalina, Lukáš; Sedlačík, Martin; Cába, Vladislav; Másilko, Jiří; Novotný, Radoslav (MDPI, 2022-05-10)
    Belite-rich cement represents one of the low carbon footprint binders. Nevertheless, its use is ac-companied by a low initial rate of hydration. This can be partially eliminated by the grinding to high specific surfaces ...
  • Degradation of P(3HB-co-4HB) Films in Simulated Body Fluids 

    Vodička, Juraj; Wikarská, Monika; Trudičová, Monika; Juglová, Zuzana; Pospíšilová, Aneta; Kalina, Michal; Slaninová, Eva; Obruča, Stanislav; Sedláček, Petr (MDPI, 2022-05-13)
    A novel model of biodegradable PHA copolymer films preparation was applied to evaluate the biodegradability of various PHA copolymers and to discuss its biomedical applicability. In this study, we illustrate the potential ...
  • Microstructural Characterization of Laser Weld of Hot-Stamped Al-Si Coated 22MnB5 and Modification of Weld Properties by Hybrid Welding 

    Šebestová, Hana; Horník, Petr; Mikmeková, Šárka; Mrňa, Libor; Doležal, Pavel; Novotný, Jan (MDPI, 2021-07-14)
    The presence of Al-Si coating on 22MnB5 leads to the formation of large ferritic bands in the dominantly martensitic microstructure of butt laser welds. Rapid cooling of laser weld metal is responsible for insufficient ...
  • Stress Effect of Food Matrices on Viability of Probiotic Cells during Model Digestion 

    Skoumalová, Petra; Hoová, Julie; Ryšávka, Petr; Márová, Ivana (MDPI, 2021-07-05)
    The aim of this study was to evaluate the influence of model (alcohol, sugar, salt, protein and acid) and real foods and beverages on the viability of probiotics during incubation and artificial digestion. Viability of ...
  • Biotechnological Conversion of Grape Pomace to Poly(3-hydroxybutyrate) by Moderately Thermophilic Bacterium Tepidimonas taiwanensis 

    Kouřilová, Xenie; Pernicová, Iva; Vidláková, Michaela; Krejčiřík, Roman; Mrázová, Kateřina; Hrubanová, Kamila; Kryžánek, Vladislav; Nebesářová, Jana; Obruča, Stanislav (MDPI, 2021-09-01)
    Polyhydroxyalkanoates (PHA) are microbial polyesters that have recently come to the forefront of interest due to their biodegradability and production from renewable sources. A potential increase in competitiveness of PHA ...
  • G-quadruplexes in H1N1 influenza genomes 

    Brázda, Václav; Porubiaková, Otília; Cantara, Alessio; Bohálová, Natália; Coufal, Jan; Bartas, Martin; Fojta, Miroslav; Mergny, Jean-Louis (Springer Nature, 2021-01-24)
    Background: Influenza viruses are dangerous pathogens. Seventy-Seven genomes of recently emerged genotype 4 reassortant Eurasian avian-like H1N1 virus (G4-EA-H1N1) are currently available. We investigated the presence and ...
  • Facile Preparation of Porous Microfiber from Poly-3-(R)-Hydroxybutyrate and Its Application 

    Kundrát, Vojtěch; Matoušková, Petra; Márová, Ivana (MDPI, 2020-01-20)
    In this study, we described the development of a simplified wet spinning method of the production of a novel type of porous continuous fiber based on poly-3-(R)-hydroxybutyrate (PHB). The principle of this method is ...
  • The influence of quadruplex structure in proximity to p53 target sequences on the transactivation potential of p53alpha isoforms 

    Porubiaková, Otília; Bohálová, Natália; Inga, Alberto; Vadovičová, Natália; Coufal, Jan; Fojta, Miroslav; Brázda, Václav (MDPI, 2020-01-14)
    p53 is one of the most studied tumor suppressor proteins that plays an important role in basic biological processes including cell cycle, DNA damage response, apoptosis and senescence. The human TP52 gene contains alternative ...
  • Photoelectric Properties of Solar Cells Based on Perovskites 

    Novák, Vítězslav; Vanýsek, Petr; Weiter, Martin (Czech Technical University in Prague, 2018-03-13)
    Here we discuss materials and construction of particular solar cells that could be possible replacement for the current silicon-based photovoltaic cells, and methods of studying their performance. Solar cells based on the ...