Poslední příspěvky

  • Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer 

    Heger, Zbyněk; Gumulec, Jaromír; Ondrák, Aleš; Škoda, Jan; Zítka, Zdeněk; Cernei, Natalia Vladimirovna; Masařík, Michal; Zítka, Ondřej; Adam, Vojtěch (MDPI, 2016-03-17)
    Herein, we present a study focused on the determination of the influence of long-distance (53 km) bicycle riding on levels of chosen biochemical urinary and serum prostate cancer (PCa) biomarkers total prostate-specific ...
  • Platinum nanoparticles induce damage to DNA and inhibit DNA replication 

    Nejdl, Lukáš; Kudr, Jiří; Moulick, Amitava; Hegerová, Dagmar; Ruttkay-Nedecký, Branislav; Gumulec, Jaromír; Číhalová, Kristýna; Šmerková, Kristýna; Dostálová, Simona; Křížková, Soňa; Novotná, Marie; Kopel, Pavel; Adam, Vojtěch (PLOS, 2017-07-12)
    Sparsely tested group of platinum nanoparticles (PtNPs) may have a comparable effect as complex platinum compounds. The aim of this study was to observe the effect of PtNPs in in vitro amplification of DNA fragment of phage ...
  • Effect of zinc-selenium nanoparticles on microalgae scenedesmus quadricauda 

    Strejčková, Aneta; Koláčková, Martina; Vaněčková, Tereza; Býtešníková, Zuzana; Moulick, Amitava; Rankić, Ivan; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    The increasing industrial use of nanomaterials in recent years poses a potential risk to the environment. The first organisms that come into contact with these substances include aquatic organisms, and therefore this study ...
  • Paramagnetic Nanoparticles as a Platform for FRET-Based Sarcosine Picomolar Detection 

    Heger, Zbyněk; Cernei, Natalia Vladimirovna; Křížková, Soňa; Masařík, Michal; Kopel, Pavel; Hodek, Petr; Zítka, Ondřej; Adam, Vojtěch; Kizek, René (Nature Publishing Group, 2015-03-09)
    Herein, we describe an ultrasensitive specific biosensing system for detection of sarcosine as a potential biomarker of prostate carcinoma based on Forster resonance energy transfer (FRET). The FRET biosensor employs ...
  • Sarcosine as a potential prostate cancer biomarker – A review 

    Cernei, Natalia Vladimirovna; Heger, Zbyněk; Gumulec, Jaromír; Zítka, Ondřej; Masařík, Michal; Babula, Petr; Eckschlager, Tomáš; Stiborová, Marie; Kizek, René; Adam, Vojtěch (MDPI, 2013-07-04)
    Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that ...
  • Nanostructured Polypyrrole-Based Ammonia and Volatile Organic Compound Sensors 

    Šetka, Milena; Drbohlavová, Jana; Hubálek, Jaromír (MDPI, 2017-03-10)
    The aim of this review is to summarize the recent progress in the fabrication of efcient nanostructured polymer-based sensors with special focus on polypyrrole. The correlation between physico-chemical parameters, mainly ...
  • Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells 

    Lacková, Zuzana; Buchtelová, Hana; Buchtová, Žaneta; Adam, Vojtěch; Zítka, Ondřej (Mendel University in Brno, 2017-12-31)
    In this study, the effect of selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells (PNT1A, 22RV1 and PC3) was observed. Synthetic standards of 3,4-dihydroxybenzaldehyde and naringenin ...
  • Molecular imprinting technology for targeted analysis of proteins 

    Hutařová, Jitka; Vaněčková, Tereza; Vaculovičová, Markéta; Adam, Vojtěch (Mendel University in Brno, 2017-12-31)
    Molecular imprinting has appeared to be an effective technique for creating of selective recognition sites in synthetic polymers. This procedure comprises polymerization of monomer in a presence of target molecules (template). ...
  • Sarcosine degradation pathway is involved in the epigenetics of prostate cells 

    Strmiska, Vladislav; Michálek, Petr; Buchtelová, Hana; Lacková, Zuzana; Guráň, Roman; Křížková, Soňa; Vaníčková, Lucie Pompeiano; Zítka, Ondřej; Stiborová, Marie; Eckschlager, Tomáš; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    It has been shown that sarcosine suplementation stimulates the proliferation of prostate cells and also their invassiveness. In present study we show that enzymes conected with sarcosine conversion to glycine (sarcosine ...
  • Antioxidant response of arabidopsis thaliana to ZnSe-nanoparticles, selenium and zinc ions 

    Koláčková, Martina; Moulick, Amitava; Klejdus, Bořivoj; Húska, Dalibor (Mendel University in Brno, 2017-12-31)
    The impact of zinc selenide nanoparticles (ZnSe-NPs) on plants is still unknown. The intention of this work was to compare phytotoxicity of ZnSe-NPs and selenium and zinc ions in 100, 250 and 500 M concentrations. Young ...
  • Antimicrobial activity of CdTe QDs modified with lanthanides on pseudomonas aeruginosa 

    Jelínková, Pavlína; Koudelková, Zuzana; Kopel, Pavel; Moulick, Amitava; Adam, Vojtěch (Mendel University in Brno, 2017-12-31)
    The aim of this study is to obtain data based on an experimental procedure and check the effectiveness of some antibacterial agents against pathogenic bacteria. In the present experiment, two different nanoparticles (Cadmium ...
  • Surface PEGylation and PASylation to regulate nanoparticle interactions with biological environment 

    Tesařová, Barbora; Dostálová, Simona; Hynek, David; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    Many researchers are developing nanocarriers in order to minimalize side effects of cytotoxic drugs during cancer treatment via chemotherapy. Nanocarriers can serve as a suitable platform for targeted drug delivery. To ...
  • Fluorescence imaging for evaluation of water availability to plants 

    Vaněčková, Tereza; Hynková, Lenka; Kryštofová, Olga; Adam, Vojtěch; Vaculovičová, Markéta (Mendel University in Brno, 2017-12-31)
    The aim of this study is to investigate the applicability of fluorescence imaging for monitoring of the abilities of various water-retention additives to supply water to plants protecting them against drought. Rhodamine B ...
  • hNET as a target for neuroblastoma nanomedicine 

    Charousová, Markéta; Dostálová, Simona; Haddad, Yazan Abdulmajeed Eyadh; Strmiska, Vladislav; Křížková, Soňa; Hynek, David; Milosavljević, Vedran; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    Chemotherapy often results in various side effects, which can negatively affect health. Neuroblastoma, one of the most common types of childhood cancer, is but one of the examples, where side effects of chemotherapeutic ...
  • Determination of hydroxyproline using ion-exchange liquid chromatography with vis detector and high performance liquid chromatography with fluorescence detector 

    Lacková, Zuzana; Cernei, Natalia Vladimirovna; Štěrbová, Dagmar; Haddad, Yazan Abdulmajeed Eyadh; Rozíková, Veronika; Komprda, Tomáš; Zítka, Ondřej (Mendel University in Brno, 2017-12-31)
    The first aim of the experiment was an optimization of the method for determination of hydroxyproline in a pig skin using high-performance liquid chromatography with fluorescence detector (HPLC-FLD) and ion-exchange liquid ...
  • Spiropyran-zinc interaction characterized by fluorescence spectrometry and capillary electrophoresis with laser-induced fluorescence detection 

    Němcová, Natálie; Šmerková, Kristýna; Remeš, Marek; Vaculovičová, Markéta; Adam, Vojtěch (Mendel University in Brno, 2017-12-31)
    Zinc is an important biogenic element which is able to connect with indicators such as a spiropyran. The spiropyran is known for its fluorescent character and selectivity towards zinc ions (and some other metal ions, e.g. ...
  • The comparison of effect of zinc sulphate and zinc oxide nanoparticles on plants 

    Štuříková, Helena; Kryštofová, Olga; Hedbávný, Josef; Adam, Vojtěch (Mendel University in Brno, 2017-12-31)
    Zinc oxide nanoparticles are one of the most versatile materials, due to their diverse properties, functionalities, and applications. Their potencial in agriculture is also not negligible. The zinc in form of nanoparticles ...
  • Characterization of upconversion nanoparticles by fluorescence spectrometry and capillary electrophoresis 

    Vaněčková, Tereza; Zítka, Jan; PhD, Antonín Hlaváček,; Adam, Vojtěch; Vaculovičová, Markéta (Mendel University in Brno, 2017-12-31)
    Upconversion nanoparticles (UCNPs) are a novel class of luminescent tags for applications in life and material sciences. Unlike traditional fluorophores, UCNPs exhibit emission of shorter wavelength under near-infrared ...
  • Apoferritin-mediated doxorubicin internalization through transferrin receptor 1 

    Krausová, Kateřina; Dostálová, Simona; Hynek, David; Křížková, Soňa; Adam, Vojtěch; Heger, Zbyněk (Mendel University in Brno, 2017-12-31)
    This work is aimed at the possibilities of targeted drug delivery into the tumour tissue. This approach can greatly reduce the otherwise serious side effects of conventional treatment - systemic toxicity. For this purpose, ...
  • Antioxidant activity of yoghurt supplemented with natural additives 

    Ananbeh, Hanadi Abd Al Rahman Ali; Voběrková, Stanislava; Kumbár, Vojtěch (Mendel University in Brno, 2017-12-31)
    The aims of this study were the estimation of difference in physiochemical properties and antioxidant activity of yoghurts supplemented by different natural additives. In addition, the changes in physiochemical properties ...

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