Now showing items 1-4 of 4

  • Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery 

    Blažková, Iva; Nguyen, Hoai Viet; Dostálová, Simona; Kopel, Pavel; Stanisavljevic, Maja; Vaculovičová, Markéta; Stiborová, Marie; Eckschlager, Tomáš; Kizek, René; Adam, Vojtěch (MDPI, 2013-06-27)
    Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation ...
  • The Role of Metallothionein in Oxidative Stress 

    Ruttkay-Nedecký, Branislav; Nejdl, Lukáš; Gumulec, Jaromír; Zítka, Ondřej; Masařík, Michal; Eckschlager, Tomáš; Stiborová, Marie; Adam, Vojtěch; Kizek, René (MDPI, 2013-03-15)
    Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule. They cause the molecule to become highly reactive. The free radicals are also known to play a dual role in ...
  • Sarcosine as a potential prostate cancer biomarker – A review 

    Cernei, Natalia Vladimirovna; Heger, Zbyněk; Gumulec, Jaromír; Zítka, Ondřej; Masařík, Michal; Babula, Petr; Eckschlager, Tomáš; Stiborová, Marie; Kizek, René; Adam, Vojtěch (MDPI, 2013-07-04)
    Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that ...
  • Serum metallothioneins in childhood tumours – A potential prognostic marker 

    Kruseová, Jarmila; Hynek, David; Adam, Vojtěch; Kizek, René; Průša, Richard; Hraběta, Jan; Eckschlager, Tomáš (MDPI, 2013-06-06)
    Metallothioneins (MT) are low molecular weight, cysteine-rich proteins maintaining metal ions homeostasis. They play a role in carcinogenesis and may also cause chemoresistance. The aim of the study was to explore the ...