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Determination of Critical Parameters of Drug Substance Influencing Dissolution: A Case Study
(Hindawi Publishing Corporation, 2014-09-15)
The purpose of this study was to specify critical parameters (physicochemical characteristics) of drug substance that can affect dissolution profile/dissolution rate of the final drug product manufactured by validated ...
The Role of Concentration and Solvent Character in the Molecular Organization of Humic Acids
(MDPI AG, 2016-10-21)
The molecular organization of humic acids in different aqueous solutions was studied over a wide concentration range (0.01–10 g/dm3). Solutions of humic acids were prepared in three different media: NaOH, NaCl, and NaOH ...
Accumulation of Poly(3-hydroxybutyrate) Helps Bacterial Cells to Survive Freezing
Accumulation of polyhydroxybutyrate (PHB) seems to be a common metabolic strategy adopted by many bacteria to cope with cold environments. This work aimed at evaluating and understanding the cryoprotective effect of PHB. ...
Quantitative Raman Spectroscopy Analysis of Polyhydroxyalkanoates Produced by Cupriavidus necator H16
We report herein on the application of Raman spectroscopy to the rapid quantitative analysis of polyhydroxyalkanoates (PHAs), biodegradable polyesters accumulated by various bacteria. This theme was exemplified for ...