Now showing items 1-2 of 2

  • G-quadruplexes in the Archaea Domain 

    Brázda, Václav; Luo, Yu; Bartas, Martin; Kaura, Patrik; Porubiaková, Otília; Šťastný, Jiří; Pečinka, Petr; Verga, Daniela; Da Cunha, Violette; S. Takahashi, Tomio; Forterre, Patrick; Myllykallio, Hannu; Fojta, Miroslav; Mergny, Jean-Louis (MDPI, 2020-09-21)
    The importance of unusual DNA structures in the regulation of basic cellular processes is an emerging field of research. Amongst local non-B DNA structures, G-quadruplexes (G4s) have gained in popularity during the last ...
  • G4Killer web application: a tool to design G-quadruplex mutations 

    Brázda, Václav; Kolomazník, Jan; Mergny, Jean-Louis; Šťastný, Jiří (2020-05-15)
    G-quadruplexes (G4) are important regulatory non-B DNA structures with therapeutic potential. A tool for rational design of mutations leading to decreased propensity for G4 formation should be useful in studying G4 functions. ...