Preparation and biosensing performance of porous-alumina-assisted gold nanostructures on substrates
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Date
2016-12-01
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Mark
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Elsevier
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Abstract
Gold based nanosize structures such as nanoparticles and nanowires are considered as important building blocks for nanotechnology to be used for construction of sensing micro- and nanodevices because of their excellent optical, electrical and mechanical properties. Here we synthesize via porous-alumina-assisted anodizing and electrodeposition perfect arrays of gold nanodots and nanorods, upright standing, spatially separated and highly aligned on a conductive substrate, which are expected to have exceptional performance in nanoscale electronic, optoelectronics and sensing applications. Biosensing potential of the nanostructured electrodes was assessed by examining electrochemical properties of a protein layer grafted on the electrode for Creactive protein (CRP) detection using CRP-antibody immobilization method with protein G intermediate layer. The laboratory prototype of immunosensor revealed reproducible, rapid and stable response with a low limit for CRP-antigen detection of 100 fg·ml-1
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Procedia Engineering. 2016, vol. 168, issue 1, p. 1188-1191.
https://www.sciencedirect.com/science/article/pii/S1877705816337183
https://www.sciencedirect.com/science/article/pii/S1877705816337183
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Peer-reviewed
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en
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
http://creativecommons.org/licenses/by-nc-nd/4.0/