Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation

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dc.contributor.authorLipový, Břetislavcs
dc.contributor.authorRaška, Filipcs
dc.contributor.authorKocmanová, Ivacs
dc.contributor.authorHanslianová, Markétacs
dc.contributor.authorHladík, Martincs
dc.contributor.authorHoloubek, Jakubcs
dc.contributor.authorBezdíček, Matějcs
dc.contributor.authorMacháček, Ctiradcs
dc.coverage.issue6cs
dc.coverage.volume7cs
dc.date.issued2021-06-18cs
dc.description.abstractInfectious complications are responsible for the majority of mortalities and morbidities of patients with critical burns. Although bacteria are the predominant etiological agents in such patients, yeasts and fungi have become relatively common causes of infections over the last decade. Here, we report a case of a young man with critical burns on 88% TBSA (total body surface area) arising as a part of polytrauma. The patient's history of orthotopic liver transplantation associated with the patient's need to use combined immunosuppressant therapy was an additional complication. Due to deep burns in the forearm region, we have (after a suitable wound bed preparation) applied a new bi-layered dermal substitute. The patient, however, developed a combined fungal infection in the region of this dermal substitute caused by Trichoderma longibrachiatum and Aspergillus fischeri (the first case ever reported). The infection caused the loss of the split-thickness skin grafts (STSGs); we had to perform repeated hydrosurgical and mechanical debridement and a systemic antifungal treatment prior to re-application of the STSGs. The subsequent skin transplant was successful.en
dc.formattextcs
dc.format.extent1-10cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationJournal of Fungi. 2021, vol. 7, issue 6, p. 1-10.en
dc.identifier.doi10.3390/jof7060487cs
dc.identifier.issn2309-608Xcs
dc.identifier.other173069cs
dc.identifier.urihttp://hdl.handle.net/11012/202263
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofJournal of Fungics
dc.relation.urihttps://www.mdpi.com/2309-608X/7/6/487cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2309-608X/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectdermal substituteen
dc.subjectinfectionen
dc.subjectTrichodermaen
dc.subjectAspergillusen
dc.subjectcritical burnsen
dc.subjectliver transplantationen
dc.subjectimmunosuppressionen
dc.titleTrichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantationen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-173069en
sync.item.dbtypeVAVen
sync.item.insts2024.03.01 18:46:19en
sync.item.modts2024.03.01 18:14:02en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Pokročilé biomateriálycs
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