Left Ventricular Myocardial Septal Pacing in Close Proximity to LBB Does Not Prolong the Duration of the Left Ventricular Lateral Wall Depolarization Compared to LBB Pacing

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dc.contributor.authorČurila, Karolcs
dc.contributor.authorJurák, Pavelcs
dc.contributor.authorVernooy, Kevincs
dc.contributor.authorJastrzebski, Marekcs
dc.contributor.authorWaldauf, Petrcs
dc.contributor.authorPrinzen, Fritscs
dc.contributor.authorHalámek, Josefcs
dc.contributor.authorSušánková, Markétacs
dc.contributor.authorZnojilová, Luciecs
dc.contributor.authorSmíšek, Radovancs
dc.contributor.authorKarch, Jakubcs
dc.contributor.authorPlešinger, Filipcs
dc.contributor.authorMoskal, Pawelcs
dc.contributor.authorHeckman, Luukcs
dc.contributor.authorMizner, Jancs
dc.contributor.authorViščor, Ivocs
dc.contributor.authorVondra, Vlastimilcs
dc.contributor.authorLeinveber, Pavelcs
dc.contributor.authorOsmančík, Pavelcs
dc.coverage.issue1cs
dc.coverage.volume8cs
dc.date.issued2021-12-07cs
dc.description.abstractBackground: Three different ventricular capture types are observed during left bundle branch pacing (LBBp). They are selective LBB pacing (sLBBp), non-selective LBB pacing (nsLBBp), and myocardial left septal pacing transiting from nsLBBp while decreasing the pacing output (LVSP). Study aimed to compare differences in ventricular depolarization between these captures using ultra-high-frequency electrocardiography (UHF-ECG). Methods: Using decremental pacing voltage output, we identified and studied nsLBBp, sLBBp, and LVSP in patients with bradycardia. Timing of ventricular activations in precordial leads was displayed using UHF-ECGs, and electrical dyssynchrony (e-DYS) was calculated as the difference between the first and last activation. The durations of local depolarizations (Vd) were determined as the width of the UHF-QRS complex at 50% of its amplitude. Results: In 57 consecutive patients, data were collected during nsLBBp (n = 57), LVSP (n = 34), and sLBBp (n = 23). Interventricular dyssynchrony (e-DYS) was significantly lower during LVSP 16 ms (21; 11), than nsLBBp 24 ms (28; 20) and sLBBp 31 ms (36; 25). LVSP had the same V1d-V8d as nsLBBp and sLBBp except for V3d, which during LVSP was shorter than sLBBp; the mean difference 9 ms (16; 1), p = 0.01. LVSP caused less interventricular dyssynchrony and the same or better local depolarization durations than nsLBBp and sLBBp irrespective of QRS morphology during spontaneous rhythm or paced QRS axis. Conclusions: In patients with bradycardia, LVSP in close proximity to LBB resulted in better interventricular synchrony than nsLBBp and sLBBp and did not significantly prolong depolarization of the left ventricular lateral wall.en
dc.formattextcs
dc.format.extent1-10cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationFrontiers in Cardiovascular Medicine. 2021, vol. 8, issue 1, p. 1-10.en
dc.identifier.doi10.3389/fcvm.2021.787414cs
dc.identifier.issn2297-055Xcs
dc.identifier.orcid0000-0003-0413-3604cs
dc.identifier.orcid0000-0001-7267-4408cs
dc.identifier.other175204cs
dc.identifier.researcheridF-5329-2017cs
dc.identifier.scopus57188873046cs
dc.identifier.urihttp://hdl.handle.net/11012/203233
dc.language.isoencs
dc.publisherFrontierscs
dc.relation.ispartofFrontiers in Cardiovascular Medicinecs
dc.relation.urihttps://www.frontiersin.org/article/10.3389/fcvm.2021.787414cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2297-055X/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectleft bundle branch pacingen
dc.subjectleft septal myocardial pacingen
dc.subjectUHF-ECGen
dc.subjectdyssynchronyen
dc.subjectdepolarization durationen
dc.titleLeft Ventricular Myocardial Septal Pacing in Close Proximity to LBB Does Not Prolong the Duration of the Left Ventricular Lateral Wall Depolarization Compared to LBB Pacingen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-175204en
sync.item.dbtypeVAVen
sync.item.insts2024.03.01 18:46:05en
sync.item.modts2024.03.01 18:14:09en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
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