Thin TiO2Coatings by ALD Enhance the Cell Growth on TiO2Nanotubular and Flat Substrates

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dc.contributor.authorMotola, Martincs
dc.contributor.authorČapek, Jancs
dc.contributor.authorZazpe Mendioroz, Raúlcs
dc.contributor.authorBačová, Janacs
dc.contributor.authorHromádko, Luděkcs
dc.contributor.authorBrůčková, Lenkacs
dc.contributor.authorNg, Siow Wooncs
dc.contributor.authorHandl, Jiřícs
dc.contributor.authorSpotz, Zdeněkcs
dc.contributor.authorKnotek, Petrcs
dc.contributor.authorBaishya, Kaushikcs
dc.contributor.authorMajtnerová, Pavlínacs
dc.contributor.authorPřikryl, Jancs
dc.contributor.authorSopha, Hanna Ingridcs
dc.contributor.authorRoušar, Tomášcs
dc.contributor.authorMacák, Jancs
dc.coverage.issue9cs
dc.coverage.volume3cs
dc.date.accessioned2021-04-19T14:54:53Z
dc.date.available2021-04-19T14:54:53Z
dc.date.issued2020-09-21cs
dc.description.abstractThe present work exploits Ti sheets and TiO2 nanotube (TNT) layers and their surface modifications for the proliferation of different cells. Ti sheets with a native oxide layer, Ti sheets with a crystalline thermal oxide layer, and two kinds of TNT layers (prepared via electrochemical anodization) with a defined inner diameter of 12 and 15 nm were used as substrates. A part of the Ti sheets and the TNT layers was additionally coated by thin TiO2 coatings using atomic layer deposition (ALD). An increase in cell growth of WI-38 fibroblasts (>50%), MG-63 osteoblasts (>30%), and SH-SY5Y neuroblasts (>30%) was observed for all materials coated by five cycles ALD compared to their uncoated counterparts. The additional ALD TiO2 coatings changed the surface composition of all materials but preserved their original structure and protected them from unwanted crystallization and shape changes. The presented approach of mild surface modification by ALD has a significant effect on the materials’ biocompatibility and is promising toward application in implant materials.en
dc.formattextcs
dc.format.extent6447-6456cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationACS Applied Bio Materials. 2020, vol. 3, issue 9, p. 6447-6456.en
dc.identifier.doi10.1021/acsabm.0c00871cs
dc.identifier.issn2576-6422cs
dc.identifier.other167263cs
dc.identifier.urihttp://hdl.handle.net/11012/196522
dc.language.isoencs
dc.publisherAmerican Chemical Societycs
dc.relation.ispartofACS Applied Bio Materialscs
dc.relation.urihttps://pubs.acs.org/doi/10.1021/acsabm.0c00871cs
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2576-6422/cs
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/cs
dc.subjectTiO2 nanotube layersen
dc.subjectTi sheetsen
dc.subjectatomic layer depositionen
dc.subjectcoatingsen
dc.subjectcell growthen
dc.titleThin TiO2Coatings by ALD Enhance the Cell Growth on TiO2Nanotubular and Flat Substratesen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-167263en
sync.item.dbtypeVAVen
sync.item.insts2021.04.19 16:54:53en
sync.item.modts2021.04.19 16:14:39en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Pokročilé nízkodimenzionální nanomateriálycs
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Sdílená laboratoř RP1cs
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Energie budoucnosti a inovacecs
thesis.grantorVysoké učení technické v Brně. Fakulta strojního inženýrství. Ústav materiálových věd a inženýrstvícs
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Sdílená laboratoř RP1
Energie budoucnosti a inovace
Pokročilé nízkodimenzionální nanomateriály
Ústav materiálových věd a inženýrství