First Complete Genome of the Thermophilic Polyhydroxyalkanoates Producing Bacterium Schlegelella thermodepolymerans DSM 15344

Simple item page
dc.contributor.authorMusilová, Janacs
dc.contributor.authorKouřilová, Xeniecs
dc.contributor.authorBezdíček, Matějcs
dc.contributor.authorLengerová, Martinacs
dc.contributor.authorObruča, Stanislavcs
dc.contributor.authorŠkutková, Helenacs
dc.contributor.authorSedlář, Karelcs
dc.coverage.issue4cs
dc.coverage.volume13cs
dc.date.accessioned2021-04-15T14:54:09Z
dc.date.available2021-04-15T14:54:09Z
dc.date.issued2021-01-12cs
dc.description.abstractSchlegelella thermodepolymerans is a moderately thermophilic bacterium capable of producing polyhydroxyalkanoates (PHA) – biodegradable polymers representing an alternative to conventional plastics. Here, we present the first complete genome of the type strain S. thermodepolymerans DSM 15344 that was assembled by hybrid approach using both, long (Oxford Nanopore) and short (Illumina) reads. The genome consists of a single 3,858,501bp long circular chromosome with GC content of 70.3%. Genome annotation identified 3,650 genes in total while 3,598 open reading frames belonged to protein coding genes. Functional annotation of the genome and division of genes into clusters of orthologous groups (COG) revealed a relatively high number of 1,013 genes with unknown function or unknown COG, which reflects the fact that only a little is known about thermophilic PHA producing bacteria on a genome level. On the other hand, 270 genes involved in energy conversion and production were detected. This group covers genes involved in catabolic processes which suggests capability of S. thermodepolymerans DSM 15344 to utilize and biotechnologically convert various substrates such as lignocellulose-based saccharides, glycerol, or lipids. Based on the knowledge of its genome, it can be stated that S. thermodepolymerans DSM 15344 is a very interesting, metabolically versatile bacterium with great biotechnological potential.en
dc.formattextcs
dc.format.extent1-13cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationGENOME BIOL EVOL. 2021, vol. 13, issue 4, p. 1-13.en
dc.identifier.doi10.1093/gbe/evab007cs
dc.identifier.issn1759-6653cs
dc.identifier.other167680cs
dc.identifier.urihttp://hdl.handle.net/11012/196505
dc.language.isoencs
dc.publisherOxford University Presscs
dc.relation.ispartofGENOME BIOL EVOLcs
dc.relation.urihttps://academic.oup.com/gbe/article/13/4/evab007/6081016cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1759-6653/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectde novo assemblyen
dc.subjecthybrid assemblyen
dc.subjectONTen
dc.subjectfunctional annotationen
dc.subjectPHAen
dc.titleFirst Complete Genome of the Thermophilic Polyhydroxyalkanoates Producing Bacterium Schlegelella thermodepolymerans DSM 15344en
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-167680en
sync.item.dbtypeVAVen
sync.item.insts2021.05.27 12:53:23en
sync.item.modts2021.05.27 12:14:21en
thesis.grantorVysoké učení technické v Brně. Fakulta chemická. Ústav chemie potravin a biotechnologiícs
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
evab007.pdf
Size:
324.22 KB
Format:
Adobe Portable Document Format
Description:
evab007.pdf
Download
Collections
Ústav chemie potravin a biotechnologií
Ústav biomedicínského inženýrství