Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

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dc.contributor.authorLízal, Františekcs
dc.contributor.authorElcner, Jakubcs
dc.contributor.authorBělka, Miloslavcs
dc.contributor.authorJedelský, Jancs
dc.contributor.authorJícha, Miroslavcs
dc.coverage.volume143cs
dc.date.accessioned2017-11-01T17:00:22Z
dc.date.available2017-11-01T17:00:22Z
dc.date.issued2016-11-15cs
dc.description.abstractThe presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.en
dc.formattextcs
dc.format.extent1-4cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationEPJ Web of Conferences. 2016, vol. 143, p. 1-4.en
dc.identifier.doi10.1051/epjconf/201714302067cs
dc.identifier.issn2100-014Xcs
dc.identifier.other131497cs
dc.identifier.urihttp://hdl.handle.net/11012/70127
dc.language.isoencs
dc.publisherEDP Sciencescs
dc.relation.ispartofEPJ Web of Conferencescs
dc.relation.urihttps://www.epj-conferences.org/articles/epjconf/abs/2017/12/epjconf_efm2017_02067/epjconf_efm2017_02067.htmlcs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2100-014X/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectaerosol depositionen
dc.subjecthuman lungsen
dc.subjecthuman airwaysen
dc.subjectcomputational fluid mechanicsen
dc.subjectexperimenten
dc.titlePrediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulationen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-131497en
sync.item.dbtypeVAVen
sync.item.insts2021.02.26 00:57:40en
sync.item.modts2021.02.26 00:15:12en
thesis.grantorVysoké učení technické v Brně. Fakulta strojního inženýrství. EÚ-odbor termomechaniky a techniky prostředícs
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